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Lecanemab-Labeled Amyloid Plaques Identified in Down Syndrome

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Extensive binding of lecanemab to brain blood vessels observed in Down syndrome postmortem brain tissue analysis

Differences ID’d in Tau Burden in Down Syndrome, Alzheimer Disease

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Differences in spatial distribution, timing, magnitude of tau burden seen for two genetic forms of Alzheimer disease

Mortality Up 25-Fold for Congenital Heart Disease With Down Syndrome

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Mortality rate twofold higher for patients with CHD with Down syndrome versus without

Walking Linked to Improved Cognitive Outcomes in Down Syndrome

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Walking interactions can improve physical health and cognitive and executive function in adults with Down syndrome

Children With Down Syndrome Experience More Medical Imaging

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More medical imaging, including CT, fluoroscopy, angiography, nuclear medicine, reported for those with Down syndrome, especially in those younger than 1 year

PET Changes Similar for Alzheimer Disease, Down Syndrome

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No difference seen in global PET amyloid burden between asymptomatic with Down syndrome, asymptomatic mutation carriers

Incidence of Diabetes Increased for Youth With Down Syndrome

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Incidence rates of type 1 and type 2 diabetes higher in individuals with Down syndrome

Upper Airway Stimulation Effective in Teens With Down Syndrome, OSA

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73.2 percent of patients had AHI of less than 10 events/hour at 12 months; improvement also seen in quality of life

Health Supervision Discussed for Children With Down Syndrome

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Guidance provided for counseling of pregnant women with prenatal diagnosis, care of the child from infancy through adolescence

Children With Down Syndrome at Higher Risk for Leukemia

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Risk particularly high for acute myeloid leukemia before age 5 years