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Tag: Diabetes: Drugs

Use of aspirin

Use of Common Meds Tied to Lower Lung Cancer Mortality

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Combined use of aspirin, statins, metformin tied to lower lung cancer risk and mortality
A recall of the widely used diabetes drug metformin was announced by drug maker Apotex due to possible high levels of N-Nitrosodimethylamine

Metformin Recalled Due to Potential Cancer-Causing Chemical

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Recall is for all lots of metformin hydrochloride extended-release tablets 500 mg from Apotex
Insulin and other biologic drugs

FDA: Insulin Among Drugs Transitioned to Biological Products

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New regulatory pathway for biologic drugs allows for approval of biosimilars, interchangeable versions
Initiation of therapy with sodium-glucose cotransporter-2 inhibitors for type 2 diabetes mellitus is not associated with an increased risk for urinary tract infection events compared with initiation of other second-line antidiabetic medications

SGLT-2 Inhibitor Use Not Linked to Increased Risk for UTI Events

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Findings seen in propensity-matched cohorts versus receipt of DPP-4 inhibitors or GLP-1 agonists
Metformin use may promote a survival benefit in individuals with post-pancreatitis diabetes mellitus

Metformin May Cut Mortality Risk in Post-Pancreatitis Diabetes

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Survival benefit not seen with ever use of metformin for pancreatic cancer-related diabetes
For adults with type 2 diabetes initiating second-line antidiabetic medications (ADM)

Second-Line Antidiabetic Meds May Impact Cardiovascular Risk

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Cardiovascular risk increased with sulfonylureas and basal insulin versus newer classes of ADM
For older adults

DPP-4I Not Tied to Increased Risk of Acute Pancreatitis in Seniors

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Among adults with heart disease, risk increased with DPP-4I versus thiazolidinedione not sulfonylureas
Children exposed to metformin in utero have an increased risk of being overweight at age 4 years

Exposure to Metformin In Utero Ups Risk of Being Overweight

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Findings among children of women with polycystic ovary syndrome on metformin during pregnancy
In women with type 2 diabetes

No Link Found for Metformin or Statins and Ovarian Cancer

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Findings based on a Finnish study involving a national cohort of women with type 2 diabetes
Antidiabetes treatment discontinuation rates are higher for obese individuals undergoing bariatric surgery

Bariatric Surgery Linked to Discontinuing Diabetes Meds

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Six-year antidiabetes treatment initiation rate also much lower after bariatric surgery