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The U.S. Preventive Services Task Force recommends screening for major depressive disorder in children aged 12 to 18 years

USPSTF Issues Final Recs on Youth Depression Screening

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Screening recommended for those aged 12 to 18; insufficient evidence to assess for children aged ≤11
The U.S. Preventive Services Task Force recommends depression screening in the general adult population

USPSTF Recommends Depression Screening for All Adults

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Recommendation applies to adults aged 18 years and older, including pregnant, postpartum women
Depressive symptoms seem to be associated with coronary artery calcium in older men and women

Depressive Symptoms Linked to Coronary Artery Calcium

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Negative association with CAC severity in women; nonlinear U-shaped association for men
Premature menopause may increase a woman's later risk of depression

Premature Menopause Tied to Risk of Depression Later in Life

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Research suggests longer estrogen exposure might have protective effect
Experimental mood induction changes interleukin-18 levels and is associated with changes in central opioid neurotransmission

Experimental Mood Induction Impacts IL-18 Levels

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Experimental sadness increases IL-18, with changes more pronounced in depressed volunteers
Early childhood depression is associated with cortical gray matter development in late school age and early adolescence

Childhood Depression Tied to Cortical Gray Matter Development

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Alterations in gray matter volume loss, thinning in association with major depressive disorder
For patients with major depressive disorder

CYP2C19 Polymorphisms Impacts Citalopram Metabolism

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CYP2C19*2 polymorphism seems to contribute to interindividual variability in CIT metabolism
Cognitive behavioral therapy and antidepressants could both be equally effective as stand-alone treatments for major depressive disorder

Cognitive Therapy, Meds Equally Effective for Major Depression

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Researchers find both treatments can benefit patients with major depressive disorder
More than one in four doctors-in-training may be depressed

Depression Not Uncommon Among Resident Physicians

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Grueling medical training may help explain finding
Depression is independently associated with increased risk of readmission for acute exacerbation of chronic obstructive pulmonary disease

Depression Ups Readmission Odds for COPD Exacerbation

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Reduced one-year readmission with in-hospital tobacco cessation counseling