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The U.S. Food and Drug Administration on Tuesday approved the nasal spray medication esketamine -- a relative of the club drug and anesthetic ketamine -- for use against severe depression. Sold as Spravato

FDA Approves Ketamine-Like Drug for Severe Depression

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Drug available through restricted distribution system, must be administered in certified medical office
For overweight adults with depression

Studies Look at Ways to Reduce Depressive Episodes in Obese

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Integrated intervention associated with decline in body mass index, depressive symptoms
For patients with acne

AAD: Isotretinoin Exposure for Acne Not Linked to Depression Risk

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Acne patients with, without isotretinoin exposure had no significant difference in depression frequency
Social media use does not predict later depressive symptoms among adolescents or college undergraduates

Teens’ Social Media Use Does Not Predict Later Depression

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Rather, teen girls with more depression symptoms may use social media more
For patients receiving maintenance hemodialysis

Sertraline Tops CBT for Reducing Depression in Dialysis Patients

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Engagement intervention on treatment acceptance has no effect on acceptance of depression treatment
Women working extra-long hours and men and women working weekends have increased depressive symptoms

Atypical Temporal Work Patterns Linked to Depressive Symptoms

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Women working extra-long hours, men and women working weekends have more depressive symptoms
Several unique characteristics are linked with depression at different time points before and after giving birth

Some Characteristics Unique to Depression Before, After Birth

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Background traits tied to chronic depression; delivery experience tied to early postpartum depression
In older adults

CVD Does Not Modify Depression-Mortality Link in Elderly

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Depression tied to higher death risk in older adults; CVD explains just small fraction of excess mortality
An expert panel for the U.S. Food and Drug Administration has endorsed a drug for major depressive disorder that is a close relative to ketamine.

FDA Panel Backs Ketamine-Like Drug for Depression

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Esketamine is a nasal spray that targets different pathways in the brain than other antidepressants do
The U.S. Preventive Services Task Force recommends that clinicians provide or refer counseling interventions for pregnant or postpartum women at increased risk for perinatal depression. This recommendation forms the basis of a final recommendation statement published in the Feb. 12 issue of the Journal of the American Medical Association.

USPSTF Recommends Counseling to Prevent Perinatal Depression

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Clinicians should provide counseling or referral to high-risk pregnant, postpartum women