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Tag: Dementia

Concentrations of cerebrospinal fluid β42-amyloid 42 derived from new immunoassays may show improved agreement with visual flutemetamol F18-labeled positron emission tomography assessment

Benefits for New Immunoassays for Measuring Aβ42 in CSF

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May show improved correlation with mass spectrometry reference measurement procedure
Systemic inflammation in midlife is associated with future neurodegeneration and cognitive aging

Midlife Systemic Inflammation Tied to Late-Life Brain Volume

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Smaller hippocampal, Alzheimer's signature region volumes seen 24 years after inflammation noted
Mid-adulthood hypertension is associated with increased risk of dementia among women but not men

Mid-Adulthood HTN Tied to Higher Dementia Risk in Women

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Midlife onset of hypertension predicts 73 percent higher dementia risk versus stable normotension
Nursing home use increases with increasing cognitive impairment category

Nursing Home Use Up With Cognitive Impairment Category

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One-year mortality especially high for those with prevalent dementia and any nursing home use
Magnesium levels

Magnesium Levels Tied to Dementia Risk

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Both too high and too low of levels tied to increased dementia risk
For older adults

No Link for Cardiovascular Meds Use, Cognitive Impairment

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No link for impaired cognition, antihypertensive, antithrombotic, lipid-modifying agent use
Lithium in drinking water is associated with the incidence of dementia in a nonlinear pattern

Lithium in Drinking Water Linked to Dementia Incidence

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Significantly reduced incidence of dementia in those exposed to more than 15.0 µg/L
Seniors who spend less time each night in rapid eye movement sleep may be more likely to develop dementia as they age

Less REM May Indicate Higher Dementia Risk in Seniors

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For every 1 percent drop in sleep's REM phase, a 9 percent jump in odds for cognitive decline
Visual dysfunction at baseline is associated with poor cognitive function among older U.S. adults

Visual Dysfunction Tied to Poor Cognitive Function in Seniors

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Association identified using data from two nationally representative samples
Lifetime costs of care are substantially increased for individuals with dementia

Families Shoulder Majority of Costs Related to Dementia Care

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Reducing functional decline or behavioral and psychological symptoms leads to lower lifetime costs