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Tag: Dementia

Frail kidney transplant recipients have lower cognitive scores than nonfrail recipients four years after transplant

Cognitive Scores After Kidney Transplant Tied to Frailty

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Cognitive function first improved then declined 1 to 4 years after transplant in frail recipients
Frailty and Alzheimer disease-related brain changes independently contribute to dementia status

Frailty Could Increase Susceptibility for Dementia

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Authors say frailty should be considered in clinical care, management of Alzheimer dementia
In older adults

High Levels of Activity, Motor Ability Linked to Better Cognition

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Findings seen in older adults; independent correlations remained for those with Alzheimer disease
Breakdown of the blood-brain barrier may be an early biomarker of cognitive dysfunction

Breakdown of Blood-Brain Barrier May Drive Dementia

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Leaky brain capillaries tied to cognitive dysfunction, independent of protein markers for dementia
Patients with hypertension with progression of periventricular white matter hyperintensities have an increased risk for incident mild cognitive impairment

Risk for MCI Up With Progressive Cerebral Small Vessel Disease

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Patients with hypertension with progressive cSVD have increased risk for mild cognitive impairment
The number of people living with dementia worldwide more than doubled from 1990 to 2016

Number of People With Dementia Rose Twofold From 1990 to 2016

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Overall, 28.8 million disability-adjusted life years due to dementia; 6.4 million attributed to modifiable risks
Both restrictive and obstructive lung disease are associated with an increased risk for incident dementia and mild cognitive impairment

Restrictive, Obstructive Lung Disease Linked to Dementia Risk

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Associations seen for both Alzheimer's disease-related dementia and cerebrovascular etiologies
For sedentary adults at risk for cognitive decline

Exercise Promotes Executive Functioning in Sedentary Adults

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Significant improvements seen in executive functioning for those at risk for cognitive decline
Type 2 diabetes is associated with declines in verbal memory and fluency among older community-dwelling adults

T2DM Linked to Decline in Verbal Memory, Fluency in Older Adults

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Brain atrophy does not appear to mediate the diabetes-cognition relationship
When using brief cognitive assessments

Dementia Often Misclassified With Brief Cognitive Assessments

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Only consistent predictor of overall misclassification was absence of informant-rated poor memory