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Tag: Dementia

Population-Level Interventions Cost-Effective for Reducing Risk for Dementia

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Interventions could reduce risk factors for dementia, resulting in cost-savings and gain in quality-adjusted life years

Plasma Biomarkers of Alzheimer Neuropathy Linked to Dementia Risk

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Significant associations seen for all Alzheimer disease plasma biomarkers in late life with late-life dementia

Amyloid Probability Score 2 Has High Diagnostic Accuracy for Alzheimer Disease

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Diagnostic accuracy 73 percent for dementia specialists compared with 91 percent using the APS2

Hormone-Modulating Therapy May Reduce Dementia Risk in Breast Cancer

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Greatest reduction seen for women aged 65 to 74 years who self-identify as Black

Benzodiazepines Not Tied to Higher Dementia Risk in Older Adults

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However, potential class-dependent associations may exist

Metformin, SGLT2 Inhibitors Exhibit Significantly Lower Dementia Risk

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Metformin displayed lowest risk for dementia across diverse antidiabetics, while α-glucosidase inhibitors had highest risk

Nightmares in Midlife May Point to Future Cognitive Decline, Dementia

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Findings seen in middle-aged and older adults from the general population, free from Parkinson disease

Models Constructed to Predict Decline Over Time in MCI, Mild Dementia

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Hypothetical patients with MCI, baseline MMSE of 28, CSF Aβ1-42 of 925 pg/mL predicted to reach MMSE of 20 after 6.0 years

Dementia With Lewy Bodies Risk Down With α-1 Adrenergic Receptor Antagonists

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Risk for developing DLB was lower for men newly started on Tz/Dz/Az compared with those taking tamsulosin or 5ARI

First Responders With More Debris Exposure Have Higher Risk of Early Dementia

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Findings among World Trade Center responders and incidence of dementia at <65 years of age