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After one year of therapy with lumacaftor-ivacaftor in a real-world setting

Lumacaftor-Ivacaftor Aids Cystic Fibrosis in Real-World Setting

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Improved lung function, increased BMI, reduced need for IV antibiotics seen after one year of therapy
Potential anaphylactic or anaphylactoid reactions have been associated with insertion of peripherally inserted central catheters using the Sherlock tip locating system

Anaphylactic Reactions Tied to PICC Insertion With Magnetic Tip

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Anaphylactic, anaphylactoid reactions linked to PICC insertion using Sherlock tip locating system
For patients with cystic fibrosis

Key Cystic Fibrosis Pathogens Reduced With Ivacaftor Use

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Ivacaftor use linked to reductions in P. aeruginosa rates, prevalence of S. aureus, Aspergillus species
Adding clinical variables improves the accuracy of lung allocation score for transplant candidates

Adding Clinical Variables Aids in Lung Allocation for Transplants

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New variables ID the sickest waitlist candidates with cystic fibrosis, chronic obstructive pulmonary disease
The indication for a cystic fibrosis treatment

FDA Expands Cystic Fibrosis Treatment Approval to Children Ages 6 to 12

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Symdeko previously approved for patients ≥12 years with cystic fibrosis and certain genetic mutations
For patients with cystic fibrosis

Cytomegalovirus Linked to Faster Progression of Cystic Fibrosis

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Faster progression to end-stage lung disease observed among patients with CMV IgG positivity
Lumacaftor/ivacaftor treatment is generally safe and well tolerated for children aged 2 to 5 years with cystic fibrosis homozygous for the F508del-CFTR mutation

Drug Combo Tolerated in Younger Children With Cystic Fibrosis

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Lumacaftor/ivacaftor safe in children ages 2 to 5 with cystic fibrosis homozygous for F508del-CFTR
In infants with cystic fibrosis

Inhaling Hypertonic Saline May Aid Infants With Cystic Fibrosis

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The preventive treatment is safe and may provide clinical benefits in first year of life
Triple therapy with VX-659 or VX-445 combined with tezacaftor-ivacaftor shows promise for the treatment of adult patients with cystic fibrosis who have mutations in the cystic fibrosis transmembrane conductance regulator

Triple Combo Regimens May Address Cause of Cystic Fibrosis

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Promising results for VX-659-, VX-445-tezacaftor-ivacaftor for cystic fibrosis with mutations in CFTR
For children with cystic fibrosis and early Pseudomonas aeruginosa infection

Azithromycin Cuts Pulmonary Exacerbation in CF With Early Pa

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Risk of pulmonary exacerbation down for children with cystic fibrosis, early Pseudomonas aeruginosa