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Tag: Crohn’s Disease

Patients with moderate-to-severe Crohn's disease who haven't responded to other treatments may benefit from the drug ustekinumab (Stelara)

Ustekinumab Shows Promise in Crohn’s Disease

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Medication potentially helpful in those for whom other treatments haven't worked
Crohn's disease appears to have at least two distinct genetic subtypes

Two Genetic Subtypes of Crohn’s Disease Identified

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Findings may help explain why the disease is so tough to treat, researchers say
For Chinese patients with Crohn's disease

2 mg/kg/day Azathioprine Best for Crohn’s in Chinese Patients

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Significantly higher complete remission rate and response rate with 2 mg/kg/day than 1 mg/kg/day
Smoking increases the risk that Crohn's disease patients will experience clinical recurrence after bowel surgery

Smokers More Prone to Relapse After Crohn’s Surgery

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Research supports mercaptopurine for smokers, but not for nonsmokers
For females with Crohn's disease

Oral Contraceptive Use Ups Surgery Risk in Crohn’s

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Long-term use of oral contraceptives, especially combination type, linked to increased surgery risk
Tonsillectomy is associated with increased risk of developing Crohn's disease

Review Links Tonsillectomy to Risk of Crohn’s Disease

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No correlation seen for tonsillectomy and risk of development of ulcerative colitis
The U.S. Food and Drug Administration has approved its second-ever "biosimilar" drug

FDA Approves Inflectra as ‘Biosimilar’ to Remicade

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For adults with Crohn's, rheumatoid arthritis, or psoriasis
For patients with Crohn's disease

Risk of Reoperation Up With Perianal Lesions in Crohn’s

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Increased risk of reoperation and abdominal reoperation with perianal lesions
For patients with Crohn's disease

Side-to-Side Isoperistaltic Strictureplasty Helpful in Crohn’s

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Age at diagnosis and surgery, family history, smoking are independent risk factors for recurrence
For adult patients with refractory Crohn's disease with impaired quality of life

HSCT Not Linked to Sustained Remission in Refractory Crohn’s

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More patients undergoing HSCT able to discontinue treatment for at least three months