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Tag: Crohn’s Disease

FDA Approves Omvoh for Moderately to Severely Active Crohn Disease

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Approval based on results from phase 3 VIVID-1 trial, in which end points of clinical remission and endoscopic response were met at one year

Early Anti-TNFα Therapy Cuts Perianal Fistula Complications in Pediatric Crohn Disease

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Odds of complications significantly reduced with early anti-TNFα therapy, especially in those with perianal lesions

Study Compares Surgical Techniques for Crohn Disease

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Longest length of stay, increased odds of wound complications seen for small bowel resection versus strictureplasty and combined approach

Risankizumab Noninferior, Superior to Ustekinumab for Crohn Disease

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Risankizumab noninferior for clinical remission at week 24, superior for endoscopic remission at week 48

Top-Down Treatment Superior for Crohn Disease

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One-year outcomes better with early combined infliximab + immunomodulator vs. accelerated step-up treatment

Higher Use of Any Rx Medications Seen Years Before IBD Diagnosis

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Findings strongest for Crohn disease with ties to multisystem organ involvement

Persistent Fluorinated Chemicals Tied to Higher Risk for Inflammatory Bowel Disease

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Odds for Crohn disease and ulcerative colitis increased with higher serum perfluoroalkyl and polyfluoroalkyl substance levels up to 10 years before diagnosis

Histologic Inflammation With IBD Tied to Serious Infections

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Authors say achieving histologic remission for both Crohn disease and ulcerative colitis may reduce the risk for serious infections

Inflammatory Bowel Disease Increases Risk for Later Arrhythmias

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Findings seen for inflammatory bowel disease overall, as well as individual diseases

COVID-19 May Raise Risk for Immune Disorders like Alopecia and Crohn’s, New Study Finds

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A new study suggests people with a history of COVID-19 may face increased odds for autoimmune and autoinflammatory disorders, including alopecia, Crohn’s disease and vasculitis.