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Active cigarette smokers and individuals with chronic obstructive pulmonary disease have up-regulation of angiotensin converting enzyme II expression in the lower airways

Risk for Severe COVID-19 May Be Up in People With COPD, Smokers

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COPD patients, smokers have up-regulation of ACE-2, the cellular entry receptor for SARS-CoV-2
Chronic obstructive pulmonary disease is an independent risk factor for lung cancer incidence

COPD Independent Risk Factor for Lung Cancer

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Risk for lung cancer higher for never smokers with COPD, ever smokers with or without COPD
A once-daily

Triple Therapy Cuts Mortality in Patients With Symptomatic COPD

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All-cause mortality risk significantly lower for triple-drug regimen versus one of two dual-drug regimens
Many individuals undergoing low-dose computed tomography lung cancer screening have spirometry findings consistent with chronic obstructive pulmonary disease

Spirometry Suggests COPD for Many at Lung Cancer Screening

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57 percent have spirometry findings consistent with COPD, 67 percent do not have prior history of COPD
Lay health coaches may improve inhaler technique and adherence for low-income patients with chronic obstructive pulmonary disease

Health Coaches Improve Inhaler Use in COPD Patients

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Significant improvements in inhaler adherence, technique seen for low-income patients
Asthma and chronic obstructive pulmonary disease are associated with an increased risk for rheumatoid arthritis

Asthma, COPD Linked to Higher Risk for Rheumatoid Arthritis

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Risk for rheumatoid arthritis up after adjustment for covariates, including smoking pack-years/status
Daily integrated care conferences are associated with shorter length of stay for patients admitted with chronic obstructive pulmonary disease exacerbations at a community hospital

Daily Care Conferences May Cut Length of Stay in COPD Patients

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Study looked at average LOS in patients with COPD exacerbations treated at two community hospitals
For adults with exacerbation of chronic obstructive pulmonary disease

Antibiotics, Corticosteroids Beneficial in COPD Exacerbations

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Independent of exacerbation severity, antibiotics tied to increased resolution, less treatment failure
People with HIV are more likely to have chronic obstructive pulmonary disease and are diagnosed with the disease at a younger age than people who are HIV-negative

COPD Incidence Higher in People With HIV

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People with HIV have 34 percent higher rate of COPD than those without; smoking may be to blame
An integrated approach using data from the Chronic Obstructive Pulmonary Disease Genetic Epidemiologic study could identify individuals with possible or probable COPD as well as definite COPD

Expansion of Diagnostic Criteria Proposed for COPD

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Expanded diagnostic criteria used to classify individuals with possible, probable, definite COPD