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Rivaroxaban can prevent venous thromboembolism in cancer patients at increased risk

ASH: Rivaroxaban Prevents Blood Clots in At-Risk Cancer Patients

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Risk for patients in rivaroxaban group reduced during the on-treatment period
Among older patients with polycythemia vera

Recommended Therapies for Polycythemia Vera Underused

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Phlebotomy and hydroxyurea tied to improved survival, lower risk for thrombosis in older patients
The use of a clinical decision support system in the emergency department can improve outpatient management for patients with acute pulmonary embolism

Clinical Decision Support System Ups Outpatient PE Management

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Home discharge rate increased at intervention sites; no increase in return visits, adverse outcomes
A patient-centered education bundle intervention can reduce nonadministration of venous thromboembolism prophylaxis

Patient Education Ups VTE Prophylaxis in Hospital Setting

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Targeted patient-centered intervention reduces nonadministration of pharmacologic prophylaxis
A diagnostic strategy based on pretest clinical probability assessment

Diagnostic Strategy Can Rule Out PE in Pregnant Women

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Strategy includes clinical probability assessment, D-dimer, lower-limb compression ultrasound, CTPA
Among patients undergoing total knee arthroplasty

Aspirin, Anticoagulants Similarly Prevent VTE After TKA

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In patients having total knee arthroplasty, aspirin non-inferior for venous thromboembolism, death
The risk of recurrence after incident venous thromboembolism is high

Risk of Venous Thromboembolism Recurrence High

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At 6 months, rates for provoked, unprovoked, cancer-related VTE are 6.8, 6.92, 9.06 per 100 person-years
Rivaroxaban does not lower risk of symptomatic venous thromboembolism and related death in medical patients after hospital discharge

No Clear Benefit for Rivaroxaban After Hospital Discharge

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Incidence of major bleeding low with rivaroxaban, but clot risk not lower
Transfeminine individuals have increased rates of venous thromboembolism compared with cisgender men and cisgender women

Transfeminine Persons Have Increased VTE Incidence

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More pronounced differences in VTE, ischemic stroke for those who initiated hormone tx during follow-up
For women

VTE Linked to Acute Decline in Physical Function in Women

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Greater difference in physical decline for women specifically reporting pulmonary embolism