Tag: Clinical Trials
Report Questions Benefit of FDA Accelerated Approval Pathway
112 of the 253 authorized drugs have not been confirmed as clinically effective; 24 of these have been on market more than five years
Should Changes Made to Clinical Trials During Pandemic Be Kept?
Changes were recommended to preserve potential patient benefit while minimizing risks associated with COVID-19
WHO Calls for Global Registry of Human Genome Editing
Studies involving human genome editing should be made public, even though it would not necessarily stop unprincipled scientists
Socioeconomic Deprivation Linked to Worse Survival in Cancer Trials
Overall, progression-free, and cancer-specific survival worse for participants from areas with highest socioeconomic deprivation
Guidance Offered for Improving Diversity in Multiple Myeloma Trials
Ways to improve representation of African Americans in clinical trials could be extrapolated to other underrepresented groups
Globalization of Cancer Trials Tied to Lower Enrollment of Blacks
Significant inverse correlation identified between proportion of patients enrolled outside the U.S. and disparity score
NIH Halts Trial of Convalescent Plasma for Mild COVID-19
While the treatment seemed safe, no significant differences in outcomes were seen between patients receiving convalescent plasma or placebo
Racial/Ethnic Minorities Underrepresented in Vaccine Trials
In adult trials, White patients and women are overrepresented; White patients account for 77.9 percent of participants
COVID-19 Vaccines Adapted to Fight Variants Will Not Require Long Clinical Trials: FDA
Most makers of approved COVID-19 vaccines have said they plan to adapt their vaccines to tackle variants
Oncology Clinical Trials Decline During Pandemic
Decline in trial launches could have long-term negative impact, authors say