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Tag: Clinical Trials

Barriers Persist for Enrolling Women in Cardiology Clinical Trials

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Eight barriers discussed include differential care, ageism, logistical barriers, lack of diversity in clinical trial leadership

Enrollment in Cancer Treatment Trials Largely Unchanged by Pandemic

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However, there was a significant decrease in enrollment for cancer control and prevention trials

Report Questions Benefit of FDA Accelerated Approval Pathway

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112 of the 253 authorized drugs have not been confirmed as clinically effective; 24 of these have been on market more than five years

Should Changes Made to Clinical Trials During Pandemic Be Kept?

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Changes were recommended to preserve potential patient benefit while minimizing risks associated with COVID-19

WHO Calls for Global Registry of Human Genome Editing

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Studies involving human genome editing should be made public, even though it would not necessarily stop unprincipled scientists

Socioeconomic Deprivation Linked to Worse Survival in Cancer Trials

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Overall, progression-free, and cancer-specific survival worse for participants from areas with highest socioeconomic deprivation

Guidance Offered for Improving Diversity in Multiple Myeloma Trials

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Ways to improve representation of African Americans in clinical trials could be extrapolated to other underrepresented groups

Globalization of Cancer Trials Tied to Lower Enrollment of Blacks

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Significant inverse correlation identified between proportion of patients enrolled outside the U.S. and disparity score

NIH Halts Trial of Convalescent Plasma for Mild COVID-19

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While the treatment seemed safe, no significant differences in outcomes were seen between patients receiving convalescent plasma or placebo

Racial/Ethnic Minorities Underrepresented in Vaccine Trials

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In adult trials, White patients and women are overrepresented; White patients account for 77.9 percent of participants