Tag: Clinical Trials
Eligibility Criteria May Influence Disparity in Multiple Myeloma Trial Enrollment
Blacks and other race subgroups have higher multiple myeloma trial ineligibility rates compared with Whites
Race, Ethnicity Reporting in Pediatric Clinical Trials Has Improved
Asian American, Black, and Hispanic populations underrepresented compared with U.S. population demographics
Outcomes Worse for Black Patients With Head, Neck Cancer in Clinical Trials
Outcomes worse for Black versus White patients enrolled in clinical trials that minimize access to care, socioeconomic status confounders
Females, Some Minorities Underrepresented in COVID-19 Clinical Trials
Females underrepresented in treatment trials, while Asian, Black participants underrepresented in prevention trials
Preprint, Peer-Reviewed Pairs of Studies Generally Concordant
Sample sizes, primary end points, interpretations mainly concordant for studies published on medRxiv, then in journals
Study Explores Impact of FDA Approval of Aducanumab on Trial Participation
Individuals who were independently aware of the FDA decision demonstrated reduced willingness to participate
Second Death in Trial of Experimental Alzheimer Drug Raising Concerns
Doctors suspect that by stripping away amyloid deposits, lecanemab weakens blood vessels and leaves them vulnerable to bleeds
Most Pivotal Trials of New Drugs Recruit From Low-, Middle-Income Countries
Percentage of participants recruited from low-, middle-income countries was 8, 36, and 17 percent for cancer, cardiovascular, neurology trials
FDA Oversight of Clinical Trials Described as ‘Grossly Inadequate’
Article describes inadequate oversight relating to development of COVID-19 vaccines and predating the pandemic
Many U.S. Adults Unlikely to Enroll in Drug Trials for Dementia Prevention
Those with a family history or higher self-perceived risk are more likely to participate
