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Greater transparency is being promoted in clinical research

Greater Transparency Being Promoted in Research

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Move toward greater transparency has extended beyond medication products to other interventions
For patients with cancer

Finances Affect Patient Decisions About Cancer Clinical Trials

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Greater financial concern linked to lower self-efficacy and preparation for decision making
Educational content delivered before the first oncologist visit

Patient Education Ups Willingness to Consider Clinical Trials

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PRE-ACT increases knowledge, reduces attitudinal barriers; linked to greater patient satisfaction
There's been a sharp rise in the number of industry-funded clinical trials and a significant decline in those financed by the U.S. government in recent years

Industry Outpacing NIH in Funding Research

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Analysis finds studies paid for by private sector increasing, while U.S.-sponsored trials decline
Pharmaceutical industry-sponsored studies are more likely to report favorable estimates in cost-effectiveness analysis of drugs used in breast cancer treatment

Industry-Led Oncology Trials May Inflate Cost-Effectiveness

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Breast cancer cost-effectiveness analyses show favorable estimates with industry funding
Large clinical studies that are sponsored by industry are more likely to report favorable outcomes and less likely to report unfavorable outcomes than those sponsored by the National Institutes of Health

Cardiovascular Trial Sponsorship Significantly Impacts Findings

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Favorable outcomes seven times more likely in industry- versus NIH-sponsored trials
Lower-income patients with cancer are less likely to participate in clinical trials

Lower-Income Cancer Patients Less Likely to Participate in Trials

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Trial participation decreases with decreasing annual household income
Independent researchers couldn't reproduce the findings of more than half of 100 experiments previously published in three prominent psychology journals

Challenges in Replicating Results of Psychology Studies

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Reason to suspect similar issues across disciplines, researcher says
In a position statement published online July 20 in the Journal of Clinical Oncology

ASCO Calls for Cancer Trials to Include More Seniors

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Older adults react differently to treatment, oncology group notes
Among institutional review board members

Progress in Reporting Conflict of Interest Among IRB Members

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Percentage of members who felt another member didn't disclose financial relationships down '05 to '14