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Dozens of scientific papers from the laboratory of well-known heart researcher Piero Anversa contain fraudulent data

Harvard: Heart Researcher’s Papers Contain Fraudulent Data

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31 scientific publications from the laboratory of Piero Anversa contain falsified and/or fabricated data
Accepted manuscripts for observational studies have better adherence to the Strengthening the Reporting of Observational Studies in Epidemiology checklist compared with rejected manuscripts

Accepted Manuscripts Meet More Criteria for Research Reporting

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Certain items, such as objectives, translation of risk poorly reported in most observational research
Industry employees are often involved in the design

Industry-Funded Trials Often Involve Employees in Studies

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Many trials published in high-impact journals involve funder, academic author in study design, reporting
A major non-profit advocacy group is asking that a large government trial comparing treatments for sepsis be shut down.

Critics Demand Stop to ‘Guinea Pig’ Sepsis Clinical Trial

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Clovers trial seeks to determine which IV fluids, vasopressors combo works best to curb sepsis
Half of trials on the European Union Clinical Trials Register are non-compliant with the European Commission's requirement that all trials post results to the registry within 12 month of completion

Compliance With Requirement to Report Results on EUCTR Is Poor

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Half of trials on European Union Clinical Trials Register are non-compliant with requirements
The median data age in clinical trials in journals with a high impact factor is about three years at publication

Data Age in Clinical Trials Is About Three Years at Publication

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Trials funded by government were associated with significantly longer time to publication
Published trials have larger treatment effects than unpublished trials

Publication Characteristics Tied to Treatment Effects

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Larger tx effects for published versus unpublished trials; larger effects in non-English publications
Few participants in clinical trials have strong concerns about the risks of data sharing

Most Research Participants Not Concerned About Data Sharing

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93 percent very or somewhat likely to allow their data to be shared with university scientists
Few participants in clinical trials have strong concerns about the risks of data sharing

Most Research Participants Not Concerned About Data Sharing

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93 percent were very or somewhat likely to allow their data to be shared with university scientists
Rural and urban cancer patients with uniform care access through participation in a SWOG (formerly the Southwest Oncology Group) treatment trial have similar outcomes

Similar Outcomes for Rural, Urban Cancer Patients in SWOG Trials

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Few differences between rural, urban patients in cancer outcomes with uniform access to cancer care