Tag: Clinical Trials
Data Age in Clinical Trials Is About Three Years at Publication
Trials funded by government were associated with significantly longer time to publication
Publication Characteristics Tied to Treatment Effects
Larger tx effects for published versus unpublished trials; larger effects in non-English publications
Most Research Participants Not Concerned About Data Sharing
93 percent very or somewhat likely to allow their data to be shared with university scientists
Most Research Participants Not Concerned About Data Sharing
93 percent were very or somewhat likely to allow their data to be shared with university scientists
Similar Outcomes for Rural, Urban Cancer Patients in SWOG Trials
Few differences between rural, urban patients in cancer outcomes with uniform access to cancer care
Tools, Methods of RCTs Can Be Adapted to Real-World Settings
3 options described for applying approaches used in randomized controlled trials to real-world data
11 Infant Deaths Halt Trial of Sildenafil in Pregnant Women
Aim of the trial was to improve blood flow to the placenta and promote fetal growth
Trials Supporting FDA Approval of Breakthrough Drugs Examined
Pivotal trials supporting these approvals often lack randomization, double-blinding, control groups
Variation in Quality of Trials for Atrial Fibrillation, Flutter
Most common trial endpoint is AF/AFL recurrence; rates of primary clinical endpoints are low
Many Organizations Not Meeting Trial Reporting Requirements
Only 19 percent of organizations use computer software to monitor compliance with Final Rule
