Tag: Clinical Trials
Adding High-Dose Chloroquine Not Advised for Severe COVID-19
High-dose versus low-dose group had higher lethality until day 13, more instances of QTc interval >500 ms
Premature Posting of Remdesivir Findings Were ‘Inconclusive’
Due to low enrollment, study was 'underpowered to enable statistically meaningful conclusions'
Enrollment Begins in NIH-Sponsored Trial of Remdesivir for COVID-19 Patients
Institutions also announce enrollment in study evaluating efficacy of sarilumab for hospitalized COVID-19 patients
Author Conflicts of Interest May Influence Cannabidiol Conclusions
Supportive conclusions seen in more studies with versus without CBD-related industry funding
Fewer Women in Cardiovascular Trials, but Representation Improving
Representation of women varies with disease and trial characteristics, but overall, men still dominate
Gefapixant Promising for Relief of Unexplained Chronic Cough
Cough frequency significantly reduced after 12 weeks of gefapixant 50 mg versus placebo in phase 2b study
Two Experimental Drugs for Rare, Inherited Alzheimer Disease Disappoint
Both drugs designed to target and neutralize amyloid beta in the brain
Visit Adherence, Visual Acuity Linked in Macular Degeneration
Late, very late groups saw fewer letters than patients in on-time group for two measures of visit adherence
Fewer Than Half of Clinical Trials Comply With Reporting Laws
Compliance with Food and Drug Administration Amendments Act of 2007 low, not improving
New Workflow Could Improve Imaging Assessment in Research
Use of a tumor response assessment core can avoid potential bias by medical oncologists in oncology trials
