Tag: Clinical Trials
Semaglutide May Reduce Craving in Alcohol Use Disorder
Phase 2 trial shows significant reduction in drinks per drinking day and weekly alcohol craving
One in Six Patients in Phase 2 Cancer Trials Receive Drug When Eventually Approved
Proportion increases when considering off-label use but drops when considering drugs with substantial clinical benefit
AI-Assisted Screening Tool Speeds Trial Eligibility Determination
Implementing AI-assisted screening tool enhances clinical trial efficiency, expedites screening process
Tecovirimat No Aid for Time to Lesion Resolution With Mpox
Additionally, interim analysis shows that the antiviral is safe but has no effect on pain among adults with mild-to-moderate clade II mpox
About One-Third Eligible for Weight Loss Drugs Meet Trial Exclusion Criteria
Most common exclusion criteria were major depressive disorder, malignant neoplasms, liver disease, uncontrolled HTN
Progression-Free Survival Improved With Nivolumab + AVD in Hodgkin Lymphoma
Longer progression-free survival seen with nivolumab + doxorubicin, vinblastine, and dacarbazine (AVD) versus brentuximab vedotin + AVD
2008 to 2022 Saw Rise in Industry-Sponsored Adult Cancer Clinical Trials
From 2018 to 2022, industry-to-federally sponsored trial ratio was 8.1
Once-Weekly Efsitora Noninferior to Degludec for Type 2 Diabetes
Once-weekly efsitora noninferior to once-daily degludec for decrease in mean glycated hemoglobin level
Quadruple Single Pill Superior for Resistant Hypertension
Reductions seen in mean office sitting systolic BP and sitting diastolic BP and in mean 24-hour ambulatory systolic BP
Depemokimab Cuts Exacerbation Rate in Eosinophilic Asthma
Annualized rate of exacerbations reduced across two randomized trials in severe asthma with eosinophilic phenotype