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Tecovirimat No Aid for Time to Lesion Resolution With Mpox

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Additionally, interim analysis shows that the antiviral is safe but has no effect on pain among adults with mild-to-moderate clade II mpox

About One-Third Eligible for Weight Loss Drugs Meet Trial Exclusion Criteria

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Most common exclusion criteria were major depressive disorder, malignant neoplasms, liver disease, uncontrolled HTN

Progression-Free Survival Improved With Nivolumab + AVD in Hodgkin Lymphoma

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Longer progression-free survival seen with nivolumab + doxorubicin, vinblastine, and dacarbazine (AVD) versus brentuximab vedotin + AVD

2008 to 2022 Saw Rise in Industry-Sponsored Adult Cancer Clinical Trials

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From 2018 to 2022, industry-to-federally sponsored trial ratio was 8.1

Once-Weekly Efsitora Noninferior to Degludec for Type 2 Diabetes

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Once-weekly efsitora noninferior to once-daily degludec for decrease in mean glycated hemoglobin level

Quadruple Single Pill Superior for Resistant Hypertension

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Reductions seen in mean office sitting systolic BP and sitting diastolic BP and in mean 24-hour ambulatory systolic BP

Depemokimab Cuts Exacerbation Rate in Eosinophilic Asthma

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Annualized rate of exacerbations reduced across two randomized trials in severe asthma with eosinophilic phenotype

Granting Waiver for Cancer Treatment Does Not Affect Safety, Efficacy Outcomes

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Similar serious adverse event rate, clinical benefit seen for patients with versus those without a waiver

NCCN: Cancer Drug Shortages Remain a Challenge for Clinicians

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89 percent of cancer centers report that cancer drugs are in short supply, most often vinblastine, etoposide, and topotecan

AI Screens Patients for Clinical Trials With Greater Accuracy Than Staff

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In addition to enhanced performance, automated screening cuts costs