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Tag: Chemotherapy

Patients with advanced head and neck cancer undergoing chemoradiotherapy and receiving metformin experience more side effects than patients not on metformin

More Side Effects With CRT Plus Metformin in Head, Neck Cancer

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Metformin group less likely to tolerate cisplatin, have grade ≥3 nausea/vomiting, hematologic toxicities
Guidelines relating to the appropriate adjuvant regimen for patients with pancreatic cancer have been updated in light of new evidence

ASCO Updates Recs on Potentially Curable Pancreatic Cancer

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Regimen of gemcitabine, capecitabine preferred in absence of concerns for toxicity, tolerance
Mindfulness practice during chemotherapy can reduce the blunting of neuroendocrine profiles typically observed in cancer patients

Mindfulness Practice Reduces Cortisol Blunting During Chemo

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Findings in colorectal cancer patients using mindfulness practice at start of chemo sessions
Combination therapy with lenalidomide

Combo Rx Plus Stem-Cell Tx Ups PFS in Multiple Myeloma

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Longer progression-free survival, but no significant difference in overall survival at four years
Loss of E-cadherin protein expression in the pretherapeutic biopsy of rectal cancer is associated with fewer metastases and improved survival

Protein Expression Predicts Rectal Cancer Outcomes

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Best prognostic value from E-cadherin expression + resection growth pattern
Maintenance therapy with cediranib for women with relapsed ovarian cancer is not detrimental to quality of life

Cediranib Tx in Relapsed Ovarian CA Doesn’t Lower Quality of Life

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Findings among women on maintenance therapy for relapsed ovarian cancer
Among patients participating in a chemotherapy drug trial

Cancer Patients Vary in Survival Benefit Needed to Justify Chemo

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And, generally, physicians are less likely to accept chemotherapy for modest survival benefit
For women with cervical cancer

Magnesium Wasting Despite Diuretic Choice in Cervical CA Tx

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Significant magnesium wasting regardless of whether furosemide or mannitol used before cisplatin
Learning to control brain waves with neurofeedback appears to help cancer survivors ease symptoms of chronic chemotherapy-induced peripheral neuropathy

Neurofeedback Aids in Reducing Chemo-Related Nerve Damage

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Clinically and statistically significant reductions in peripheral neuropathy seen following neurofeedback
For patients with small-cell lung cancer

Pravastatin Does Not Improve Survival in Small-Cell Lung Cancer

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Median overall survival of 10.6 versus 10.7 months for pravastatin versus placebo added to chemo