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Tag: Chemotherapy

Mechanisms ID’d for Curcumin Resensitization of Cancer Cells

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Compound helps turn off pathways linked to chemoresistance in pancreatic ductal adenocarcinoma
For patients with locally advanced or metastatic pancreatic carcinoma with malignant ascites

Chemo Plus Hyperthermia Active in Advanced Pancreatic Cancer

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Systemic and intraperitoneal chemotherapy + hyperthermia well tolerated and active
A cooling cap approved in 2015 for use in breast cancer patients has received expanded approval from the U.S. Food and Drug Administration.

FDA Expands Use of Cooling Cap to Cut Chemo-Related Hair Loss

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Treatment now approved for patients receiving chemotherapy for solid tumors
For patients with previously untreated stage IV or recurrent non-small-cell lung cancer

Nivolumab Doesn’t Up PFS in Stage IV or Recurrent NSCLC

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Findings in patients with previously untreated disease with PD-L1 expression level of ≥5 percent
A patient-reported outcome intervention for symptom monitoring is associated with improved overall survival for patients treated with chemotherapy for metastatic solid tumors

ASCO: Survival Up With Patient-Reported Outcomes During CA Tx

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Improved survival with patient-reported outcomes for symptom monitoring in metastatic cancer
For patients with ovarian cancer

New VTE Often Occurs During Chemo in Ovarian Cancer

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Most cases of venous thromboembolism occurred during neoadjuvant or adjuvant chemotherapy
Patients with advanced head and neck cancer undergoing chemoradiotherapy and receiving metformin experience more side effects than patients not on metformin

More Side Effects With CRT Plus Metformin in Head, Neck Cancer

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Metformin group less likely to tolerate cisplatin, have grade ≥3 nausea/vomiting, hematologic toxicities
Guidelines relating to the appropriate adjuvant regimen for patients with pancreatic cancer have been updated in light of new evidence

ASCO Updates Recs on Potentially Curable Pancreatic Cancer

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Regimen of gemcitabine, capecitabine preferred in absence of concerns for toxicity, tolerance
Mindfulness practice during chemotherapy can reduce the blunting of neuroendocrine profiles typically observed in cancer patients

Mindfulness Practice Reduces Cortisol Blunting During Chemo

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Findings in colorectal cancer patients using mindfulness practice at start of chemo sessions
Combination therapy with lenalidomide

Combo Rx Plus Stem-Cell Tx Ups PFS in Multiple Myeloma

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Longer progression-free survival, but no significant difference in overall survival at four years