Tag: Chemotherapy
VDT PACE Effective in Relapsed, Refractory Multiple Myeloma
Minimal response or more in 68.4 percent of patients, partial response or more in 54.4 percent
Oral Chemotherapy Parity Laws Offer Some Financial Protection
Decrease in estimated out-of-pocket spending at the 25th, 50th, 75th percentiles; increase at 90th, 95th
70-Gene Signature Impacts Treatment Decisions in Breast CA
70-GS linked to change in treatment decisions for intermediate-risk patients based on 21-gene assay
Mechanism ID’d for Chemo-Related Peripheral Neuropathy
Paclitaxel triggers CIPN in part by altering IP3 receptor phosphorylation, intracellular calcium flux
Ramucirumab Shows Promise in Care of Advanced Gastric Cancer
In two separate trials, hazard ratios for overall survival favor treatment with ramucirumab
Limited Evidence of Benefit for Medical Cannabinoids in Children
Strongest evidence for benefit in chemo-induced nausea, vomiting; other uses need more evidence
Cryotherapy May Prevent Chemo-Induced Neuropathy
Breast cancer patients on paclitaxel had lower incidence of peripheral neuropathy with cryotherapy
Neurotoxicity Characterized After Infusion of CD19 CAR-T Cells
Patients with severe neurotoxicity have endothelial activation, increased BBB permeability
PFS Up With Obinutuzumab-Based Tx in Follicular Lymphoma
Induction, maintenance treatment with obinutuzumab-based chemo beats rituximab
ASTRO: Standard-Dose CRT Beats Higher Dose in Stage III NSCLC
Significantly improved five-year overall survival rates with 60 Gy chemoradiation tx versus high-dose