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Tag: Chemotherapy

For women with human epidermal growth factor receptor type 2-negative breast cancer receiving anthracycline chemotherapy

ACC: Carvedilol Doesn’t Prevent Anthracycline Cardiotoxicity

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Carvedilol does not prevent reduction in LVEF in breast cancer but is linked to lower troponin I levels
From 2004 to 2014

Private Insurance Coverage of Infused Chemo Varies by Setting

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Better reimbursement at hospital outpatient depts, even though drug-level costs lower in doctor's office
Racial and ethnic disparities in the use of preoperative chemotherapy exist among patients with gastric cancer in the United States

Disparities Seen in Gastric Cancer Patients’ Receipt of Pre-Op Chemo

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Racial, ethnic disparities in treatment also affect disparities in overall survival
In patients aged 80 and older with advanced non-small-cell lung cancer

Race, Education Level Predict CRT in Very Elderly With NSCLC

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In elderly with stage III lung cancer, black race, lower-educated county tied to not receiving care
Cancer therapies have direct effects on telomere length

Cancer Therapies May Trigger Aging Phenotypes in Survivors

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Chemotherapies, radiation have direct effects on telomere length, epigenetic modifications, microRNA
For patients with advanced-stage Hodgkin's lymphoma

ASH: A+AVD Beats ABVD for Advanced Hodgkin’s Lymphoma

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Lower combined risk of progression, death, or noncomplete response with A+AVD
For heavily pre-treated patients with relapsed/refractory multiple myeloma

VDT PACE Effective in Relapsed, Refractory Multiple Myeloma

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Minimal response or more in 68.4 percent of patients, partial response or more in 54.4 percent
The adoption of state oral chemotherapy parity laws has improved financial protection for many patients

Oral Chemotherapy Parity Laws Offer Some Financial Protection

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Decrease in estimated out-of-pocket spending at the 25th, 50th, 75th percentiles; increase at 90th, 95th
The 70-gene signature assay affects treatment decisions among physicians treating patients identified as being at intermediate risk with the 21-gene assay

70-Gene Signature Impacts Treatment Decisions in Breast CA

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70-GS linked to change in treatment decisions for intermediate-risk patients based on 21-gene assay
Researchers may have uncovered the mechanism for chemotherapy-induced peripheral neuropathy related to paclitaxel

Mechanism ID’d for Chemo-Related Peripheral Neuropathy

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Paclitaxel triggers CIPN in part by altering IP3 receptor phosphorylation, intracellular calcium flux