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Tag: Chemotherapy

Among patients with cancer starting chemotherapy who are at intermediate-to-high risk

Apixaban Prevents VTE in Cancer Patients Initiating Chemotherapy

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Major bleeding occurred in more apixaban-treated than control patients
For patients with residual invasive disease after neoadjuvant chemotherapy including a taxane and trastuzumab

SABCS: T-DM1 Cuts Recurrent Invasive HER2+ Breast CA Risk

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Risk reduced with trastuzumab emtansine in those with residual invasive dz at sx after neoadjuvant chemo
For patients with CD30-positive peripheral T-cell lymphoma

ASH: A+CHP Bests CHOP for Peripheral T-Cell Lymphoma

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Median progression-free survival improved with A+CHP vs CHOP; similar incidence of adverse events
Delaying initiation of adjuvant chemotherapy in triple-negative breast cancer patients more than 30 days after surgery is associated with a decrease in survival

SABCS: Delaying Chemo Lowers Survival in Triple-Neg Breast CA

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Findings show delaying chemo over 30 days postsurgery lowers triple-negative breast cancer survival
The U.S. Food and Drug Administration recently announced the approval of Daurismo (glasdegib) tablets for use in combination with a low dose of the chemotherapy cytarabine to treat newly diagnosed acute myeloid leukemia. The treatment is indicated for patients aged 75 years or older who have comorbidities that may prevent the use of intensive chemotherapy.

FDA Approves New Treatment for Acute Myeloid Leukemia

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Randomized clinical trial showed significant improvement in overall survival with Daurismo
For premenopausal women with stage I to IIIA estrogen receptor-negative

Improved Long-Term Pregnancy Outcomes for Goserelin + Chemo

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Findings seen in premenopausal women with stage I to IIIA hormone receptor-negative breast cancer
For patients with multiple myeloma in whom treatment with lenalidomide and a proteasome inhibitor has failed

Addition of Elotuzumab Ups PFS in Refractory Multiple Myeloma

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In phase 2 trial, longer progression-free survival for elotuzumab with pomalidomide and dexamethasone
For patients with metastatic triple-negative breast cancer

Chemoimmunotherapy Ups Survival in Triple-Negative Breast Cancer

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Atezolizumab plus nab-paclitaxel prolongs progression-free survival in metastatic disease
The incidence of congestive heart failure during pregnancy is 31 percent among women with a history of cardiotoxicity associated with cancer treatment

CHF in Pregnancy Up for Cancer Survivors With Cardiac Toxicity

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Incidence of congestive heart failure at 31 percent among women with a history of cardiotoxicity
Risk of cardiotoxicity is higher for patients receiving trastuzumab and/or anthracyclines for the treatment of breast cancer

Cardiac Monitoring Needed for High-Risk Breast Cancer Patients

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Trastuzumab, certain chemo treatments increase patient risk of heart failure