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Tag: Chemotherapy

For patients with lung adenocarcinoma

Radiomic Features May Predict Response to Chemo in NSCLC

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Peritumoral, intratumoral radiomic features on baseline CT scans may predict chemo response
The current standard of care for advanced cervical cancer -- external beam radiation therapy and chemotherapy in combination with brachytherapy -- provides significantly higher overall survival over chemoradiation alone; however

Brachytherapy Boost Ups Survival in Locally Advanced Cervical Cancer

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Findings observed regardless of treatment duration; disparities for brachytherapy use seen in vulnerable populations
Tecentriq (atezolizumab) has been approved by the U.S. Food and Drug Administration to treat adults with extensive-stage small cell lung cancer.

FDA OKs Tecentriq for Extensive-Stage Small Cell Lung Cancer

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Drug now approved as first-line treatment to be used in combination with carboplatin and etoposide
The U.S. Food and Drug Administration has given its blessing to the first immunotherapy regimen for breast cancer.

FDA Approves First Immunotherapy Drug for Breast Cancer

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Combo of Tecentriq and chemo given accelerated approval for triple-negative breast cancer
Long-term cardiomyopathy risk varies by chemotherapy agent for childhood cancer survivors

Long-Term Cardiomyopathy Risk Varies by Chemo Agent

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Decreased risk seen for daunorubicin versus doxorubicin among survivors of childhood cancer
Combined modality treatment is associated with improved overall survival in pediatric patients with early-stage Hodgkin lymphoma

Chemo-Radiation Combo Tied to Higher Survival in Peds Hodgkin

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Five-year overall survival higher in patients who receive combined tx than those treated with chemo alone
Survivors of childhood Hodgkin lymphoma remain at increased risk for developing subsequent malignant neoplasms

Childhood Hodgkin Lymphoma Survivors at Risk for Later Cancers

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Survivors have 14-fold increased risk for developing a solid subsequent malignant neoplasm
The risks for therapy-related myelodysplastic syndrome or acute myeloid leukemia are elevated after chemotherapy use for solid tumors

Myelodysplastic Syndrome/AML Risk Increased After Chemo

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Since 2000, risks for therapy-related myelodysplastic syndrome, AML up after chemo for solid cancers
For patients with resected pancreatic cancer

Modified-FOLFIRINOX Beneficial in Resected Pancreatic Cancer

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Disease-free, overall survival significantly longer compared with gemcitabine, but more adverse events
For treatment of human papillomavirus-positive low-risk oropharyngeal cancer

Cisplatin Superior to Cetuximab for HPV+ Oropharyngeal Cancer

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Toxicity similar in two treatment groups at 24 months, but worse tumor control with cetuximab