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Tag: Chemotherapy

For high-risk stage 1 nonseminoma germ cell tumors of the testis

One-Cycle BE500P Seems Safe for High-Risk Early Testicular Cancer

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Malignant recurrence rate was 1.3 percent at two years for one-cycle BE500P in high-risk early-stage disease
Proton chemoradiotherapy is associated with a significantly lower risk for 90-day adverse events and a decrease in performance status during treatment compared with photon therapy

Adverse Events Decreased With Proton Chemoradiotherapy

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Relative risks lower for 90-day adverse events of at least grade 3 and 2 compared with photon therapy
Use of antioxidants and other dietary supplements before and during chemotherapy is associated with worse survival outcomes for patients with breast cancer

Antioxidant, Supplement Use May Worsen Breast Cancer Outcomes

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Disease-free, overall survival poorer with vitamin B12 use before and during chemotherapy
Obesity is associated with an increased risk for cardiotoxicity among patients receiving treatment for breast cancer

Obesity May Up Cardiotoxicity Risk From Breast Cancer Therapy

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Obesity independently associated with treatment-related cardiotoxicity in breast cancer patients
For patients with metastatic colorectal cancer

Continuing Full Induction Regimen Not Beneficial in Metastatic CRC

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Maintenance therapy shows benefit versus observation in terms of PFS but not overall survival
Adding tucatinib to trastuzumab and capecitabine is associated with improved progression-free and overall survival among heavily pretreated patients with human epidermal growth factor receptor 2-positive metastatic breast cancer

SABCS: Addition of Tucatinib Ups Survival in HER2+ Metastatic Breast Cancer

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In heavily pretreated patients, adding tucatinib versus placebo improves overall, progression-free survival
Positron emission tomography-directed therapy results in excellent outcomes for patients with stage I/II diffuse large B-cell lymphoma

ASH: PET Helps Tailor Therapy in Limited-Stage DLBCL

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Most patients had negative PET scan and completed one additional R-CHOP cycle without radiation
Endocrine therapy reduces the quality of life of breast cancer patients

Endocrine Therapy Lowers QOL for Breast Cancer Patients

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Effects of chemotherapy found to be more transient in comparison
For patients with platinum-sensitive recurrent ovarian cancer

Secondary Surgical Cytoreduction Not Superior in Ovarian Cancer

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Addition of surgery prior to chemotherapy does not prolong overall survival in recurrent ovarian cancer
For relapsed or refractory acute myeloid leukemia with mutations in the FMS-like tyrosine kinase 3 gene (FLT3)

Gilteritinib Superior in Relapsed, Refractory FLT3-Mutated AML

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Overall survival significantly longer, percentage of remission higher than with salvage chemotherapy