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Tag: Chemotherapy

For patients with locally advanced upper tract urothelial carcinoma

Chemo Ups Disease-Free Survival in Upper Tract Urothelial Cancer

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Gemcitabine-platinum combination therapy tied to improved survival after nephroureterectomy
For patients with untreated stage II or III triple-negative breast cancer

Adding Pembrolizumab May Up Response in Triple-Negative Breast Cancer

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Pathological complete response rate higher with pembrolizumab plus neoadjuvant chemotherapy
Dasatinib is associated with improved survival for pediatric patients with Philadelphia chromosome-positive acute lymphoblastic leukemia

Dasatinib Tops Imatinib for Ph+ Acute Lymphoblastic Leukemia

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Four-year cumulative risk of any relapse lower for dasatinib in the context of intensive chemotherapy
For high-risk stage 1 nonseminoma germ cell tumors of the testis

One-Cycle BE500P Seems Safe for High-Risk Early Testicular Cancer

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Malignant recurrence rate was 1.3 percent at two years for one-cycle BE500P in high-risk early-stage disease
Proton chemoradiotherapy is associated with a significantly lower risk for 90-day adverse events and a decrease in performance status during treatment compared with photon therapy

Adverse Events Decreased With Proton Chemoradiotherapy

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Relative risks lower for 90-day adverse events of at least grade 3 and 2 compared with photon therapy
Use of antioxidants and other dietary supplements before and during chemotherapy is associated with worse survival outcomes for patients with breast cancer

Antioxidant, Supplement Use May Worsen Breast Cancer Outcomes

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Disease-free, overall survival poorer with vitamin B12 use before and during chemotherapy
Obesity is associated with an increased risk for cardiotoxicity among patients receiving treatment for breast cancer

Obesity May Up Cardiotoxicity Risk From Breast Cancer Therapy

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Obesity independently associated with treatment-related cardiotoxicity in breast cancer patients
For patients with metastatic colorectal cancer

Continuing Full Induction Regimen Not Beneficial in Metastatic CRC

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Maintenance therapy shows benefit versus observation in terms of PFS but not overall survival
Adding tucatinib to trastuzumab and capecitabine is associated with improved progression-free and overall survival among heavily pretreated patients with human epidermal growth factor receptor 2-positive metastatic breast cancer

SABCS: Addition of Tucatinib Ups Survival in HER2+ Metastatic Breast Cancer

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In heavily pretreated patients, adding tucatinib versus placebo improves overall, progression-free survival
Positron emission tomography-directed therapy results in excellent outcomes for patients with stage I/II diffuse large B-cell lymphoma

ASH: PET Helps Tailor Therapy in Limited-Stage DLBCL

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Most patients had negative PET scan and completed one additional R-CHOP cycle without radiation