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Tag: Cancer: Uterine

Taxane plus platinum regimens may be a reasonable alternative to doxorubicin plus cisplatin as postoperative adjuvant chemotherapy for endometrial cancer that carries a high risk for progression

Taxane + Platinum Feasible for Adjuvant Tx in Endometrial Cancer

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Tolerability, survival similar to that for doxorubicin + cisplatin for postoperative adjuvant chemotherapy
The introduction of minimally invasive robotic surgery is associated with a significantly lower risk for severe complications among patients with early-stage endometrial cancer

Fewer Complications After MIRS Introduced for Endometrial Cancer

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Introduction of minimally invasive robotic surgery linked to reduced odds of severe complications
The incidence of uterine cancer and uterine cancer deaths has increased since 1999

Since 1999, Uterine Cancer Incidence, Mortality Up

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Incidence of uterine cancer higher among non-Hispanic black and white women; more deaths for blacks
Sentinel lymph node mapping has the lowest costs and highest quality-adjusted survival compared to both routine and selective lymphadenectomy for managing low-risk endometrial carcinoma

Sentinel Lymph Node Mapping Most Cost-Effective for Uterine CA

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Findings compared to routine, selective lymphadenectomy for low-risk endometrial cancer
Most women with postmenopausal bleeding will not be diagnosed with endometrial cancer

Most Postmenopausal Bleeding Not Associated With Cancer

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Most women with endometrial CA have bleeding, but risk of CA among those with bleeding just 9 percent
Endometrial cancer survivors have an elevated risk of various adverse long-term cardiovascular outcomes

Long-Term Cardiovascular Risk for Endometrial Cancer Survivors

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Elevated risk of various cardiovascular outcomes, including pulmonary heart disease, atrial fibrillation
For patients with human epidermal growth factor receptor 2/neu-positive uterine serous carcinoma

New Drug Combo Ups Survival in HER2/neu Uterine Serous Cancer

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Adding intravenous trastuzumab to carboplatin-paclitaxel increased progression-free survival
PapSEEK

Genetic Assay of PAP Tests May Help Dx Endometrial, Ovarian CA

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PapSEEK tests for gene mutation, aneuploidy; better detection with Tao brush intrauterine sampling
A levonorgestrel-releasing intrauterine device is effective in the majority of patients undergoing conservative treatment for low-risk endometrial cancer and complex atypical hyperplasia

Levonorgestrel IUD Feasible for Low-Risk, Early Uterine Cancer

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Majority of women responded well and returned to normal histology in six months
For women in Finland

Endometrial Ablation Doesn’t Increase Cancer Risk

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No increased risk of endometrial, breast cancer for women in Finland treated with endometrial ablation