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Tag: Cancer: Skin

Cotellic (cobimetinib) in combination with another chemotherapy

FDA Approves Cotellic for Advanced Melanoma

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For patients whose tumors express BRAF V600E or V600K mutations
Late age at natural menopause and menopausal hormone therapy use are associated with increased risk of basal cell carcinoma

Age at Menopause, Hormone Therapy Linked to BCC Risk

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Increased risk with late age at natural menopause and with any use of menopausal hormone therapy
For patients with rheumatoid arthritis and inflammatory bowel disease with prior nonmelanoma skin cancer (NMSC)

Some RA Treatments Up Second Nonmelanoma Skin Cancer Risk

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Increased risk with methotrexate, and for anti-TNF drugs in conjunction with methotrexate
The melanoma drug Yervoy (ipilimumab) can now be used to reduce the risk of the recurrence after surgery

FDA Approves Expanded Use for Melanoma Drug

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Yervoy can now be used after surgery to reduce risk of skin cancer returning
Hidradenitis suppurativa can be associated with infectious and/or neoplastic fatal complications

Fatal Case of Hidradenitis Suppurativa Described

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Case report describes fatal case of HS associated with sepsis and squamous cell carcinoma
Imlygic (talimogene laherparepvec) has been approved by the U.S. Food and Drug Administration to treat melanoma lesions of the skin and lymph nodes.

FDA Approves Imlygic for Melanoma

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Injectable drug designed to rupture and kill cancer cells
Oxidative stress inhibits metastasis by melanoma cells

Oxidative Stress Inhibits Metastasis by Melanoma Cells

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Metastasizing cells undergo metabolic changes, increasing their ability to withstand oxidative stress
A case of basal cell carcinoma has been described within a port wine stain

Case of Basal Cell Carcinoma Described Within Port Wine Stain

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Tumor described within port wine stain, without previous treatment, including radiotherapy
Nicotinamide appears to reduce non-melanoma skin cancers by 23 percent when taken twice daily

Nicotinamide Could Protect Against Some Skin Cancers

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High-risk patients who took nicotinamide daily developed fewer non-melanoma lesions
Lesion-directed screening has a similar skin cancer detection rate as total-body examination but is substantially less time-consuming

Lesion-Directed Screening Effectively Detects Skin Cancer

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Has similar detection rate as total-body examination, takes much less time