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Tag: Cancer: Skin

Imaging using fluorescence confocal microscopy analysis in the reflectance mode and with an "en face" scanning can control tumor margins of eyelid basal cell carcinoma to optimize surgical management

Confocal Microscopy Aids Surgical Removal of Tumors From Eyelid

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Current study evaluated reflectance mode, horizontal scanning for removal of eyelid basal cell carcinoma
The burden of melanoma is increasing in the United States

Melanoma Incidence, Mortality Continue to Rise in the U.S.

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Compound annual growth rate: 0.9 percent in raw incidence, 3.0 percent in in situ melanoma incidence
Pathologists have wide variability in treatment suggestions for melanocytic lesions

Pathologists Vary in Suggested Therapy for Melanocytic Lesions

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Variation may lead to undertreatment or overtreatment of melanocytic lesions
MicroRNAs (miR-203 and miR-205) could be useful prognostic markers in cutaneous squamous cell carcinoma

MicroRNAs 203 and 205 Are Prognostic in Cutaneous SCC

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miR-205 expression in tumors with pathologic features indicating poor prognosis, in invasion front
For superficial or nodular basal cell carcinoma at low-risk sites

Imiquimod Has Sustained Benefit for Basal Cell Carcinoma

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Lower treatment success for imiquimod 5 percent than surgery, but rates similar at three, five years
Alcohol intake is associated with increased risk of melanoma

Alcohol Intake Linked to Increase in Risk of Melanoma

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Correlation stronger for melanoma in relatively UV-spared sites versus UV-exposed sites
From 2000 to 2012 there was an increase in the incidence of sebaceous carcinoma

Incidence of Sebaceous Carcinoma Up From 2000 to 2012

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Higher all-cause mortality among males, blacks, and for extraocular anatomic locations
Certain patients at high risk of melanoma may benefit from more tailored skin exams

Clinical Features Can Be Used to Tailor Melanoma Screening

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A tailored surveillance program could lead to greater precision in melanoma prevention
Patients with melanoma treated with a combination of ipilimumab and nivolumab may be at risk for a potentially fatal T-cell-driven drug reaction

Myocarditis ID’d With Ipilimumab + Nivolumab in Melanoma

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Case report describes two patients who developed fatal T-cell-driven drug reaction
In an non-integrated dermatopathology practice

Use of Term ‘Rule Out’ May Delay Dermatopathology Diagnosis

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Use on requisition form linked to longer time to diagnosis, increased use of pathology stains, sections