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Tag: Cancer: Skin

Physician assistants perform more skin biopsies per case of skin cancer diagnosed and diagnose fewer melanomas in situ than dermatologists

PAs May Have Lower Diagnostic Accuracy for Melanoma

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PAs diagnose fewer melanomas in situ, perform more skin biopsies per case of skin cancer diagnosed
For patients with localized melanoma

Marital Status Tied to Earlier Presentation of Melanoma

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Being married also tied to likelihood of undergoing SLNB in lesions with Breslow thickness >1 mm
Pembrolizumab is associated with significantly longer recurrence-free survival than placebo as adjuvant therapy for high-risk stage III melanoma

Adjuvant Pembrolizumab Beneficial in Stage III Melanoma

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Pembrolizumab linked to significantly longer recurrence-free survival at 15-month follow-up
About 30 percent of indoor tanners have been screened for skin cancer

Few Indoor Tanners Have Been Screened for Skin Cancer

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Correlates of screening include older age, family history of melanoma or skin cancer, high SPF sunscreen use
Use of the diuretic hydrochlorothiazide is associated with a substantially increased risk of non-melanoma skin cancer

Hydrochlorothiazide Tied to Non-Melanoma Skin Cancer Risk

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Dose-response association seen for basal cell and especially squamous cell carcinoma
Strains of Staphylococcus epidermidis producing 6-N-hydroxyaminopurine may provide protection against skin neoplasia

S. epidermidis Producing 6-HAP May Protect From Skin Neoplasia

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6-HAP selectively inhibited proliferation of tumor lines in culture; cut incidence of UV-induced tumors in mice
The most frequent dermoscopic criteria for melanoma in situ are regression

Dermoscopic Criteria Identified for Diagnosing Melanoma in Situ

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Most frequent dermoscopic criteria for MIS are regression, atypical network, irregular dots/globules
For men with metastatic melanoma treated with targeted or immune therapy

Obesity Linked to Improved Survival in Metastatic Melanoma

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Survival benefit limited to male patients receiving targeted therapy, immunotherapy
In recent years there has been an increase in melanoma incidence

2005 to 2014 Saw Increase in Melanoma Incidence

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For males and females combined, incidence fell for those aged 15 to 44, increased for those ≥55
The incidence of squamous cell carcinoma affecting the eyelids is rising in England

Eyelid Squamous Cell Carcinoma Rate Increasing in England

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Older age and male sex, but not social deprivation, are associated with higher eyelid SCC risk