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Tag: Cancer: Skin

For men with metastatic melanoma treated with targeted or immune therapy

Obesity Linked to Improved Survival in Metastatic Melanoma

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Survival benefit limited to male patients receiving targeted therapy, immunotherapy
In recent years there has been an increase in melanoma incidence

2005 to 2014 Saw Increase in Melanoma Incidence

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For males and females combined, incidence fell for those aged 15 to 44, increased for those ≥55
The incidence of squamous cell carcinoma affecting the eyelids is rising in England

Eyelid Squamous Cell Carcinoma Rate Increasing in England

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Older age and male sex, but not social deprivation, are associated with higher eyelid SCC risk
Guidelines of care have been developed for the management of basal cell carcinoma and cutaneous squamous cell carcinoma

Guidelines of Care Developed for Skin Cancer Management

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Recommendations for basal cell carcinoma, cutaneous squamous cell carcinoma released
Patients with desmoplastic melanoma have a high level of objective tumor response to treatment with antibodies to block programmed cell death 1 (PD-1) or PD-1 ligand

High Response of Desmoplastic Melanomas to PD-1 Blockade

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Higher percentage of PD-L1-positive cells in the tumor parenchyma of desmoplastic melanomas
Fluorouracil application can reduce the risk of surgery for squamous cell carcinoma for one year among patients with a history of keratinocyte carcinomas

Fluorouracil Tied to Reduced Surgery for Squamous Cell CA

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Reduced risk of squamous cell carcinoma, but not basal cell carcinoma, for one year in at-risk veterans
Atopic dermatitis is associated with an increased risk of developing squamous cell carcinoma

Atopic Dermatitis Associated With Higher Risk of Skin Cancer

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Individuals with a history of atopic dermatitis have a higher risk of squamous cell carcinoma development
A brief educational video could be beneficial for increasing hairdresser knowledge of melanoma and self-confidence in skin lesion detection

Educational Video Helps Hairdressers Better ID Melanoma

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Significant increase in correct identification of ABCDE criteria for atypical nevi, melanoma detection
Sentinel lymph node biopsy is underused for high-risk squamous cell carcinoma of the skin

Sentinel Lymph Node Biopsy Underused in High-Risk SCC

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<0.1 percent of patients with high-risk SCC tumors underwent SLNB; 14 percent underwent dissections
About one-quarter of skin biopsies are diagnosed as melanocytic proliferation

Almost One in Four Skin Biopsies Is Melanocytic Proliferation

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83.1 percent classified as nevi, other benign proliferations such as mildly dysplastic lesions