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Tag: Cancer: Skin

From 2001 to 2016

2001 to 2016 Saw Large Increase in Mohs Surgery for Melanoma

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Regional variation considerable, with more than threefold variation between regions with highest, lowest use
Less than half of health care providers discuss sun-safe behaviors with patients

Many Providers Fail to Discuss Sun-Safe Behaviors With Patients

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Skin cancer counseling often takes backseat due to lack of time, other pressing health issues
Increased dietary vitamin A seems to be associated with a reduced risk for incident cutaneous squamous cell carcinoma

Dietary Vitamin A Intake Tied to Reduced Risk for Squamous Cell Carcinoma

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Cutaneous SCC risk reduced for highest versus lowest quintile of vitamin A, retinol, some carotenoids
Stratification of melanoma into groups based on calculated tumor area improves prognostic value over stratification using the category based on Breslow thickness

Calculated Tumor Area Has Prognostic Value for Melanoma

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Calculated tumor area is a novel, microscopic feature and a two-dimensional surrogate for tumor size
Patients with multiple primary melanomas have worse overall survival than those with a single primary melanoma

Overall Survival Worse With Multiple Primary Melanomas

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Median Breslow thickness decreased from 0.90 mm for first melanoma to 0.65 mm for second melanoma
Sharing personalized practice pattern data with physicians that is benchmarked to national data for their peers can reduce overuse of Mohs micrographic surgery among outliers

Sharing Data With Surgeons Can Reduce Overuse of Mohs Surgery

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Mean stages per case reduced; reduction in Medicare spending estimated to be $11.1 million
Elderly patients with lung cancer

Lifetime Risk for Brain Mets Up in Elderly With Three Common Cancers

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Highest incidence seen for patients with non-small cell lung cancer and triple-negative breast cancer
A short course of calcipotriol plus 5-fluorouracil treatment for actinic keratosis is associated with induction of robust T cell immunity and reduced development of squamous cell carcinoma within three years

Topical Immunotx for Actinic Keratosis May Prevent Cancer

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Fewer patients treated with calcipotriol plus 5-FU developed SCC on treated face, scalp within three years
For patients with advanced Merkel cell carcinoma

Tumor Control Durable With Pembrolizumab in Merkel Cell Cancer

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28 of 50 advanced MCC patients responded; 24-month overall survival rate was 68.7 percent
U.S. states with more physicians and a larger percentage of non-Hispanic whites have worse melanoma survival

Melanoma Survival Varies Among U.S. States

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Worse survival in states with more physicians; higher death rates in states with lower incidence