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Tag: Cancer: Rectal

Recent Decline in Risk for CRC Recurrence Seen in Stage I to III Disease

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Patients with stage III disease had a shorter time from surgery to recurrence than those with stage I disease

>10 Percent of FIT Are Unsatisfactory and Cannot Be Processed

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Fewer than half of those with an unsatisfactory FIT completed a subsequent test within 15 months

Type 2 Diabetes Linked to Increased Risk for Colorectal Cancer

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Greater associations seen for those without colonoscopy screening, with smoking history, and for recent diabetes diagnosis

Receipt of Guideline-Concordant Care Lower for Black Colorectal Cancer Patients

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Disparity explained by health insurance among those with colon and rectal cancer

Advanced Neoplasia Risk Increased at Upper Range of Negative FIT Values

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At fecal hemoglobin cutoff of 17 µg/g, sensitivity and PPV were 39 percent and specificity and NPV were 93 percent

Risk-Adapted Starting Age of CRC Screening Varies by Sex, Genetics

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Risk-adapted starting age of screening varies by 24 years for men in highest polygenic risk score decile versus women in lowest

ACG: Noninvasive Multitarget Stool RNA Test Has High Sensitivity for CRC

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mt-sRNA has sensitivity of 94 percent for detecting colorectal cancer, 46 percent for advanced adenomas

Sotorasib + Panitumumab Beneficial for Chemorefractory Metastatic CRC

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Reduced hazard ratio seen for disease progression or death with sotorasib-panitumumab versus standard care

CRC Screening Uptake No Better With Use of FIT in At-Risk Individuals

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FIT screening does not improve screening uptake and has lower rate of advanced colorectal neoplasia detection

Diabetes Severity Tied to Outcome in CRC Patients Undergoing Resection

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Worse overall, disease-free, cancer-specific survival seen for patients with diabetes with complications