Tag: Cancer: Rectal
ACG: Noninvasive Multitarget Stool RNA Test Has High Sensitivity for CRC
mt-sRNA has sensitivity of 94 percent for detecting colorectal cancer, 46 percent for advanced adenomas
Sotorasib + Panitumumab Beneficial for Chemorefractory Metastatic CRC
Reduced hazard ratio seen for disease progression or death with sotorasib-panitumumab versus standard care
CRC Screening Uptake No Better With Use of FIT in At-Risk Individuals
FIT screening does not improve screening uptake and has lower rate of advanced colorectal neoplasia detection
Diabetes Severity Tied to Outcome in CRC Patients Undergoing Resection
Worse overall, disease-free, cancer-specific survival seen for patients with diabetes with complications
More Serious Adverse Events Seen With Debulking + Systemic Therapy in Metastatic CRC
Despite significant increase in serious adverse events, no difference reported in health-related quality of life
Advanced Young-Onset Adenoma Increases Colorectal Cancer Risk
However, overall 10-year colorectal cancer incidence relatively low in veterans younger than 50 years of age
Adults Overdue for CRC Screen Rarely Receive Recommendation for Screening
Prevalence of reporting clinician recommendation was lower for non-Hispanic Asian, Black, Hispanic versus White adults
Few With CRC in Sub-Saharan Africa Receive Guideline-Concordant Care
Risk for death 3.49 times higher for those receiving no cancer treatment versus standard treatment or treatment with minor deviations
Cancer Screening Has Provided Significant Value to U.S. Population
Single-site cancer screening could save an additional 3.2 to 5.1 million life-years with perfect adherence
Gains in Colorectal Cancer Outcomes Slowing, Reversing
Since ~2010, declines in diagnoses and deaths among adults in their 50s and 60s have slowed
