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Tag: Cancer: Rectal

Combinations of four proteins from stool samples can detect colorectal cancer and advanced adenomas with higher sensitivity than hemoglobin alone

Stool-Based Protein Combos Can Improve CRC Screening

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Combo of four proteins can detect CRC, advanced adenomas, with higher sensitivity than hemoglobin
Non-alcoholic fatty liver disease is associated with development of cancer

NAFLD Linked to Increased Cancer Incidence Rate

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NAFLD strongly tied to development of hepatocellular carcinoma, CRC in males, breast cancer in females
Insurance coverage differences account for about half of the disparity in survival rates between black and white patients aged 18 to 64 years with colorectal cancer

Insurance Underlies Black-White Survival Disparity in CRC

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54 percent of excess risk of death in black colorectal cancer patients accounted for by insurance matching
Fewer than half of younger adults with colorectal cancer undergo mismatch repair deficiency of DNA testing

Use of MMR Deficiency Testing in Younger CRC Patients Is Low

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Just 43.1 percent underwent mismatch repair deficiency of DNA testing
After adoption of the Affordable Care Act

Incidence of Early-Stage Breast CA, CRC Up With ACA Adoption

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No change in incidence of locally advanced or metastatic-stage cancer after ACA adoption
Higher fiber intake after a diagnosis of nonmetastatic colorectal cancer (CRC) is associated with lower CRC-specific and overall mortality

Fiber Tied to Lower Mortality in Those With Colorectal Cancer

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Increasing fiber consumption after diagnosis may lower risk of all-cause, CRC-specific mortality
Higher HER3 expression is associated with improved survival with the addition of panitumumab treatment for patients with RAS wild-type advanced colorectal cancer

HER3 Linked to Improved Survival With Panitumumab

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Addition of panitumumab to irinotecan tied to improved survival in RAS wt advanced colorectal CA
From 2003 to 2015 there was an increase in use of robotic-assisted radical nephrectomy

Robotic Radical Nephrectomy Becoming More Common

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And robotic laparoscopy for rectal cancer resection does not reduce risk for conversion to open surgery
For patients undergoing left colon and rectal cancer resections

Oral Antibiotics Cut Risk of SSI in Colorectal CA Resection

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Adding antibiotics to mechanical bowel preparation linked to reduced rate of surgical site infection
Adding surveillance to fecal immunochemical test screening reduces colorectal cancer mortality and increases colonoscopy demand

Adding Surveillance to FIT Screening Cuts CRC Mortality

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But addition of surveillance is not cost-effective based on Dutch incremental cost-effectiveness ratio