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Home Tags Cancer: Rectal

Tag: Cancer: Rectal

Administration of a single dose of oral aspirin prior to fecal immunochemical testing does not increase test sensitivity for detecting advanced colorectal neoplasms

Oral Aspirin Does Not Up FIT Test Sensitivity for ID’ing CRC

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Sensitivity not significantly increased in aspirin versus placebo group at two cutoffs
Higher cardiorespiratory fitness is associated with a lower risk for incident lung and colorectal cancer and with a lower risk for all-cause mortality among those diagnosed with lung and colorectal cancer

Cardiorespiratory Fitness Tied to Lower Risk for Lung Cancer, CRC

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For those diagnosed with lung cancer, CRC, higher CRF tied to lower risk for subsequent death
Financial incentives do not increase response rates among patients mailed at-home colorectal cancer screening tests

Financial Incentives Do Not Boost Use of At-Home CRC Screening Tests

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$10 incentives used in the study may have been too small to garner a response
Hodgkin lymphoma survivors have an increased risk for advanced colorectal neoplasia

Colorectal Neoplasia Risk Up for Hodgkin Lymphoma Survivors

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Prevalence higher for advanced adenomas, advanced serrated lesions, serrated polyposis syndrome
Starting colorectal cancer screening at age 45 instead of 50 years seems cost-effective

Starting Colorectal Cancer Screening at Age 45 Years Is Cost-Effective

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But increasing participation for unscreened older adults would yield greater benefits at lower costs
Expert guidance has been provided on the early detection of colorectal cancer and on treatment and posttreatment follow-up; the two guidelines were recently published online in the Journal of Global Oncology.

ASCO: Guidelines Released for Early Detection, Treatment of CRC

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Stratified guidelines emphasize optimal detection methods and treatments of colorectal cancer
Onset of colorectal cancer in adults younger than 50 years is distinct from onset in patients aged 50 years or older

Distinct Etiology Found for Colorectal Cancer With Early Onset

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Patients aged 18 to 29 with early-onset colorectal cancer more likely to have signet ring histology
Many patients with young-onset colorectal cancer

Young-Onset Colorectal Cancer May Often Be Misdiagnosed

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Most patients are diagnosed at advanced stages of disease, report waiting months before seeing doctor
Single-application fecal immunochemical tests have moderate-to-high sensitivity and specificity for colorectal cancer

Single-Application FIT Moderately Sensitive, Specific for CRC

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Performance characteristics vary depending on the threshold for a positive result
Aspirin is underused to reduce the risk for colorectal cancer among patients with advanced colorectal polyps

Aspirin Underused for Advanced Colorectal Polyps

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Only 42.6 percent of 84 patients with biopsy-proven advanced colorectal polyps were taking aspirin