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Home Tags Cancer: Rectal

Tag: Cancer: Rectal

Patients with ulcerative colitis have an increased risk for colorectal cancer and colorectal cancer mortality

Colorectal Cancer Risk Still Up in Patients With Ulcerative Colitis

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Even after adjustment for tumor stage, patients with ulcerative colitis have higher risk for CRC mortality
A polygenic risk score

Polygenic Risk Score More Strongly Linked to Early-Onset CRC

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Strongest association seen for participants without a first-degree family history of colorectal cancer
For patients with metastatic colorectal cancer

Continuing Full Induction Regimen Not Beneficial in Metastatic CRC

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Maintenance therapy shows benefit versus observation in terms of PFS but not overall survival
Implementation of the Dependent Coverage Expansion (DCE) under the Affordable Care Act increased early-stage colorectal cancer (CRC) diagnosis and receipt of timely adjuvant chemotherapy for surgically resected stage IIB to IIIC CRC among DCE-eligible patients

Treatment for Younger Adults With CRC Improved Under ACA

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Timely receipt of adjuvant chemo more likely in DCE-eligible patients with resected stage IIB to IIIC CRC
Following publication of updated guidelines by the American Cancer Society recommending that the age for colorectal cancer screening be lowered to 45 years

CRC Screening Up for Ages 45 to 49 After ACS Guideline Update

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Increase in screening rates in quarters 3, 4 of 2018 versus quarter 1; no change for people in their 50s
Global burdens of colorectal cancer

Four Studies Look at Global Burden of Digestive Diseases

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Global burdens of colorectal, pancreatic, stomach cancers and inflammatory bowel disease examined
Average-risk adults between the ages of 50 and 75 years should be screened for colorectal cancer

CRC Screening Recommended for Average-Risk Adults Age 50 to 75

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CRC screening test should be selected based on discussion of benefits, harms, costs with patients
Using the GRADE system to review new evidence

Personal Colorectal Cancer Risk Should Drive Screening

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Panel issues weak recommendations for options in adults aged 50 to 79 years with no prior screening
The risk for colorectal cancer death drops with an increasing number of prediagnostic colonoscopies

Prediagnostic Colonoscopy Cuts Colorectal Cancer Death Risk

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Mortality risk drops 17 percent with one colonoscopy before diagnosis, 45 percent with three colonoscopies
A triplet combination of therapies (encorafenib

Triplet Tx Ups Survival in BRAF V600E-Mutated Colorectal Cancer

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Overall survival longer for encorafenib, cetuximab, and binimetinib combo versus standard therapy