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Tag: Cancer: Prostate

Prostate multiparametric magnetic resonance imaging is feasible for predicting prostate cancer in an unselected sample of the general population

MRI Feasible for Predicting Prostate CA in Unselected Sample

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Adjusted odds ratio of prostate cancer significantly higher for MRI score than PSA
For men with metastatic prostate cancer

DNA-Repair Gene Mutations ID’d in Metastatic Prostate Cancer

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Prevalence of 11.8 percent for germline DNA-repair gene mutations presumed to be deleterious
Compared with 2012

Docs Tending Away From Post-Prostatectomy Adjuvant RT

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Urologists in Australia less favorable toward adjuvant radiotherapy in 2015 versus 2012
Robotic-assisted laparoscopic prostatectomy is associated with reductions in positive surgical margins

Benefits for Robotic-Assisted Laparoscopic Prostatectomy

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Reduced risk of positive surgical margins versus open prostatectomy for patients with pT2 disease only
From 2011 to 2013 there was a decrease in prostate cancer diagnoses

Prostate Cancer Diagnoses Down From 2011 to 2013

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Use of active surveillance increasing, active treatment decreasing for low-risk disease
For men with metastatic prostate cancer

ADT Plus Radiotherapy Ups Survival in Metastatic Prostate CA

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Superior median, five-year OS for prostate RT plus ADT versus ADT alone in propensity score analyses
A prostate-specific antigen cut point of ≥0.4 ng/mL predicts future disease progression

PSA Cut Point of ≥0.4 ng/mL Predicts Progression

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Shows the strongest correlation between biochemical recurrence and subsequent systemic progression
For chemotherapy-naive men with metastatic castration-resistant prostate cancer

Tasquinimod Improves Radiographic PFS in mCRPC

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Does not improve overall survival in metastatic castration-resistant prostate cancer
Prostate-specific antigen levels in midlife predict future lethal prostate cancer risk

Midlife PSA Levels Predict Future Lethal Prostate Cancer

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PSA levels in midlife strongly predict future lethal prostate cancer risk in U.S. cohort
For men with prostate cancer

SBRT, Proton Beam Therapy Use Increasing for Prostate CA

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Median cost of stereotactic body radiotherapy lower than IMRT or proton beam therapy