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Tag: Cancer: Prostate

In men with advanced prostate cancer

ASCO: Abiraterone Extends Survival in Metastatic Prostate CA

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Side effects noted with use of abiraterone similar to those already found in patients taking the drug
Diagnosis of subsequent metastases is associated with substantially increased costs and medical resource use among patients initially diagnosed with localized prostate cancer

Substantial Increase in Costs With Metastases in Prostate CA

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Costs peak during month of metastases diagnosis, reaching $13,291
Testing for combined urinary PCA3 and TMPRSS2:ERG RNA can improve detection of prostate cancer

Combined Urine Test for T2:ERG, PCA3 Ups Prostate CA Detection

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Combined urinary testing can avoid unnecessary prostate biopsy, while preserving high sensitivity
Distinct clinical outcomes are seen for luminal- and basal-like prostate cancers

Distinct Outcomes for Luminal-, Basal-Like Prostate Cancers

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Luminal B prostate cancers exhibited poorest clinical prognosis in univariate, multivariate analyses
Black men appear to have a higher incidence of preclinical prostate cancer and a higher risk of metastatic progression than the general population

Black Men Have Higher Rate of Preclinical Prostate Cancer

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Also increased risk of progression to metastatic disease compared with the general population
Rates of prostate-specific antigen screening have leveled off after declining for a number of years in the United States

PSA Screening Rates Have Leveled Off in U.S.

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Decline followed recommendations from U.S. Preventive Services Task Force
Timing of the first active surveillance biopsy is not associated with increased adverse reclassification of prostate cancer

Surveillance Biopsy Timing Not Tied to Reclassification

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But PSA density and body mass index are associated with prostate cancer reclassification
Among prostate cancer patients

Yoga Helps Ease Side Effects of Prostate Cancer Treatment

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Men who attended yoga classes had less fatigue and better sexual and urinary function
Fewer than one in three men screened with the prostate-specific antigen test for prostate cancer talked about the risks and benefits of the test with their doctor

PSA Test Often Occurs Without Discussion of Benefits, Harms

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Men with lower incomes, education, and no insurance less likely to receive pretest counseling
Metformin use in combination with docetaxel chemotherapy does not significantly improve survival in patients with diabetes and metastatic castration-resistant prostate cancer

Metformin Use Does Not Increase Prostate Cancer Survival

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Drug given in combination with docetaxel chemotherapy in patients with metastatic disease