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Tag: Cancer: Pancreatic

The U.S. Preventive Services Task Force recommends against screening for pancreatic adenocarcinoma as the potential benefits do not outweigh the potential harms. These recommendations form the basis of a final recommendation statement published in the Aug. 6 issue of the Journal of the American Medical Association.

USPSTF Reaffirms Recs Against Screening for Pancreatic Cancer

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Potential benefits of screening do not outweigh potential harms in asymptomatic adults
The incidence rate of pancreatic cancer increases with rising fasting blood glucose levels

Higher Fasting Plasma Glucose May Up Pancreatic Cancer Risk

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Continuous increase in risk of pancreatic cancer with elevating fasting glucose, even within normal range
A comprehensive test is more accurate than conventional clinical and imaging criteria for identifying precancerous pancreatic cysts

Novel Test Accurately Identifies Precancerous Pancreatic Cysts

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Cyst classifier test is based on clinical and imaging features, genetic and biochemical markers
Maintenance therapy with olaparib is associated with improved progression-free survival in metastatic pancreatic cancer patients with a germline BRCA1 and/or BRCA2 mutation

ASCO: Olaparib Beats Placebo for BRCA-Related Pancreatic Cancer

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Progression-free survival significantly improved with olaparib versus placebo for metastatic disease
Many patients with noncurable pancreatic adenocarcinoma do not have a specialized cancer consultation and most do not receive cancer-directed therapy

Cancer Consultation Low in Noncurable Pancreatic Adenocarcinoma

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Likelihood of cancer-directed therapy higher for first consult with medical, radiation oncology versus surgery
Three factors can predict survival in patients with borderline resectable or locally advanced pancreatic ductal adenocarcinoma

Neoadjuvant Chemotherapy Key to Survival in Pancreatic Cancer

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Three factors independently linked to prolonged survival in BR/LA pancreatic ductal adenocarcinoma
Higher body mass index

AACR: High BMI Before 50 Raising Pancreatic Cancer Mortality

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Twenty-eight percent of pancreatic cancer deaths due to higher BMI in those born in 1970 to 1974
Tooth loss is associated with an increased risk for incident pancreatic cancer in African-American women

Tooth Loss May Up Pancreatic Cancer Risk in Black Women

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Pancreatic cancer risk increased with tooth loss, especially loss of five or more teeth
The U.S. Preventive Services Task Force (USPSTF) recommends against screening for pancreatic cancer in asymptomatic adults. These findings form the basis of a draft recommendation statement published online Feb. 5 by the USPSTF.

USPSTF Still Recommends Against Pancreatic Cancer Screening

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No evidence seen for benefits of pancreatic cancer screening, treatment of screen-detected cancer
For patients with resected pancreatic cancer

Modified-FOLFIRINOX Beneficial in Resected Pancreatic Cancer

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Disease-free, overall survival significantly longer compared with gemcitabine, but more adverse events