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Tag: Cancer: Ovarian

A jury says Johnson & Johnson must pay $4.62 billion to 22 women who allege they developed ovarian cancer after using the company's Baby Powder and Shower to Shower brand talcum powder as part of their daily feminine hygiene routine.

Jury Awards $4.62B in Johnson & Johnson Talcum Powder Lawsuit

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The award includes $550 million in compensatory damages and $4.14 billion in punitive damages
PapSEEK

Genetic Assay of PAP Tests May Help Dx Endometrial, Ovarian CA

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PapSEEK tests for gene mutation, aneuploidy; better detection with Tao brush intrauterine sampling
Vigil immunotherapy shows good tolerability for recurrent ovarian cancer patients

Vigil Immunotherapy Tolerated Well for Recurrent Ovarian CA Tx

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And, PARP 7 protein plays significant role; survival up with genetic mutations, higher expression levels
In women with type 2 diabetes

No Link Found for Metformin or Statins and Ovarian Cancer

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Findings based on a Finnish study involving a national cohort of women with type 2 diabetes
The U.S. Preventive Services Task Force recommends against screening for ovarian cancer in asymptomatic women. These findings form the basis of a final recommendation statement published in the Feb. 13 issue of the Journal of the American Medical Association.

USPSTF Recommends Against Ovarian Cancer Screening

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Among asymptomatic women, harms of screening for ovarian cancer outweigh potential benefits
Elevation in white blood cell BRCA1 promoter methylation is associated with high-grade serous ovarian cancer

BRCA1 Promoter Methylation Tied to High-Grade Serous Ovarian CA

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Elevated normal tissue BRCA1 promoter methylation associated with high-grade serous ovarian CA risk
For women with ovarian cancer who underwent both surgery and adjuvant chemotherapy

Average Cost of Care in Year After Ovarian Cancer Surgery ~$100K

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Patients bear about 3 percent of these costs in the form of out-of-pocket expenses
Qualitative computed tomography features differ between patients with BRCA-mutant high-grade serous ovarian cancer (HGSOC) and patients with BRCA wild-type HGSOC

Computed Tomography Features Vary Based on BRCA Status

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Differences seen between BRCA-mutant versus BRCA wild-type high-grade serous ovarian cancer
For patients with ovarian cancer

Hospital Volume, Quality Impact Survival in Ovarian Cancer

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Survival lower for lower volume hospitals with higher quality scores versus higher volume hospitals
The potential harms of ovarian cancer screening outweigh the benefits

USPSTF: Ovarian Cancer Screen to Be Avoided for Most Women

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Test isn't accurate enough to justify its use, U.S. Preventive Services Task Force says