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Tag: Cancer: Lung

Lung cancer screening seems to be underutilized in the community

STS: Lung Cancer Screening Underused in the Community

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All network providers were aware of the screening program; 15 percent never referred a patient
Many U.S. patients with late-stage non-small-cell lung cancer do not receive treatments that could prolong their lives

Many Advanced NSCLC Patients Not Getting Helpful Treatment

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Study found 21 percent went without therapy, even though it could boost survival
For older heavy cigarette smokers

Increasing Severity of Airflow Limitation Linked to Lung CA Risk

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Linear relationship seen in population of older heavy cigarette smokers
Chemotherapy that's been delayed due to slow recovery from non-small-cell lung cancer surgical resection can still provide real benefit to patients

Delayed Chemo After Surgery Still Beneficial in Lung Cancer

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Patient recovery may mean longer time to chemotherapy, but treatment can still have benefit
From 2000 to 2011 there were shifts in the treatment of advanced-stage non-small-cell lung cancer

2000 to 2011 Saw Shift in Treatment for Advanced NSCLC

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Rise in use of pemetrexed, erlotinib, bevacizumab; longest treatment duration with these agents
The immunotherapy atezolizumab extends the survival of previously treated non-small-cell lung cancer patients for several months and causes fewer side effects than docetaxel

Atezolizumab Effective in Late-Stage Non-Small-Cell Lung Cancer

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Drug can extend survival by several months, with fewer adverse events
A stepped care program is likely to be cost-effective for patients with head and neck cancer or lung cancer who have psychological distress

Stepped Care Likely to Be Cost-Effective in Head & Neck, Lung CA

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Mean costs lower and mean number of quality-adjusted life-years higher in intervention group
Osimertinib is more effective than platinum-pemetrexed therapy in patients with T790M-positive advanced non-small-cell lung cancer whose disease has progressed during first-line epidermal growth factor receptor tyrosine kinase inhibitor treatment

Osimertinib Bests Platinum-Pemetrexed in T790M+ NSCLC

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Significantly longer duration of progression-free survival with osimertinib vs platinum-pemetrexed
Circulating exosomes released under intermittent hypoxia conditions

Intermittent Hypoxia Promotes Lung Tumor Cell Aggressiveness

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IH-induced exosomes from mice significantly promote TC1 malignant properties
An updated index incorporating gene and molecular alterations can predict survival in non-small-cell lung cancer with brain metastases

Updated Index Predicts Survival in NSCLC With Brain Metastases

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Significant prognostic factors include four factors from earlier index, plus EGFR and ALK alterations