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Tag: Cancer: Lung

From 2000 to 2011 there were shifts in the treatment of advanced-stage non-small-cell lung cancer

2000 to 2011 Saw Shift in Treatment for Advanced NSCLC

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Rise in use of pemetrexed, erlotinib, bevacizumab; longest treatment duration with these agents
The immunotherapy atezolizumab extends the survival of previously treated non-small-cell lung cancer patients for several months and causes fewer side effects than docetaxel

Atezolizumab Effective in Late-Stage Non-Small-Cell Lung Cancer

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Drug can extend survival by several months, with fewer adverse events
A stepped care program is likely to be cost-effective for patients with head and neck cancer or lung cancer who have psychological distress

Stepped Care Likely to Be Cost-Effective in Head & Neck, Lung CA

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Mean costs lower and mean number of quality-adjusted life-years higher in intervention group
Osimertinib is more effective than platinum-pemetrexed therapy in patients with T790M-positive advanced non-small-cell lung cancer whose disease has progressed during first-line epidermal growth factor receptor tyrosine kinase inhibitor treatment

Osimertinib Bests Platinum-Pemetrexed in T790M+ NSCLC

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Significantly longer duration of progression-free survival with osimertinib vs platinum-pemetrexed
Circulating exosomes released under intermittent hypoxia conditions

Intermittent Hypoxia Promotes Lung Tumor Cell Aggressiveness

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IH-induced exosomes from mice significantly promote TC1 malignant properties
An updated index incorporating gene and molecular alterations can predict survival in non-small-cell lung cancer with brain metastases

Updated Index Predicts Survival in NSCLC With Brain Metastases

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Significant prognostic factors include four factors from earlier index, plus EGFR and ALK alterations
Pembrolizumab is associated with longer progression-free and overall survival for patients with non-small-cell lung cancer with programmed death ligand 1 expression on at least 50 percent of tumor cells

Pembrolizumab Ups Survival in NSCLC With PD-L1 Expression

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Findings in patients with advanced NSCLC with PD-L1 expression on at least 50 percent of tumor cells
Longitudinal changes in depression are associated with differences in mortality among patients with lung cancer

Changes in Depression Symptoms Tied to Mortality in Lung Cancer

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Increased risk with new-onset depression, persistent depression, but not depression symptom remission
Outpatients find lung cancer screening decision aids helpful

Lung Cancer Decision Aids Are Helpful for Patients

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Patient understanding of lung cancer screening increased after participation in focus groups
Stereotactic body radiation therapy seems to provide a significant survival advantage for older patients with early-stage non-small-cell lung cancer

ASTRO: SBRT Ups Survival in Older Early-Stage NSCLC Patients

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Findings suggest SBRT should be standard for patients treated with radiation for stage I NSCLC