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Tag: Cancer: Lung

Three assays may detect early lung cancer in blood samples using genome sequencing

ASCO: New Assays May Detect Early Lung Cancer in Blood

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Targeted sequencing, whole-genome sequencing, whole-genome bisulfite sequencing show potential
For patients with programmed death ligand 1 (PD-L1)-expressing locally advanced or metastatic non-small-cell lung cancer

ASCO: Pembrolizumab Superior for Initial Tx of Advanced NSCLC

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Improved overall survival versus chemotherapy regardless of the PD-L1 tumor proportion score
Personalizing the harm-benefit assessment of low-dose computed tomography screening for lung cancer can inform patient-centered screening decisions

Prediction Tool Helps Tailor Lung Cancer Screening to Patients

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Researchers create web-based decision tool to facilitate personalized discussions
Lung cancer incidence is higher among young women than young men

Lung Cancer Incidence Higher for Young Women Than Young Men

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Crossover in sex-specific rates among U.S. non-Hispanic whites born since 1965
In 2016

ASCO: Few Eligible Smokers Had CT Screen for Lung CA in 2016

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Most eligible smokers populated in South, which had most screening sites but low screening rate
Four lung cancer risk models perform best in selecting ever-smokers for screening

Risk Models Help Select Ever Smokers for Lung CA Screening

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Four models were well-calibrated and had higher AUCs than five that overestimated risk
Cytoskeleton-associated protein 4 appears to be a novel serodiagnostic marker for lung cancer

CKAP4 Is Novel Serodiagnostic Marker for Lung Cancer

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Serum CKAP4 levels of lung cancer patients significantly higher than those of healthy controls
For patients with non-small-cell lung cancer

Clinical Upstaging of NSCLC Seen With Each Progressive Week

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For clinical stage 1 NSCLC, 21.7 percent of patients upstaged after 1 week; 31.5 percent after 8 weeks
For metastatic non-small-cell lung cancer (NSCLC)

Adjuvant Pembrolizumab Beneficial in Metastatic NSCLC

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And, nivolumab plus ipilimumab linked to better survival in NSCLC with high tumor mutational burden
In the Midwest and Appalachia there are areas where progress against lung cancer mortality among women is lagging compared with the rest of the nation

Lag in Progress Against Lung CA Mortality in Midwest, Appalachia

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Findings based on rates among women versus steady decline seen nationally