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Tag: Cancer: Lung

For patients undergoing resection for non-small cell lung cancer

More Frequent Surveillance No Benefit After NSCLC Resection

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More frequent postsurgical surveillance is not associated with improved survival
Existing tobacco control efforts will continue to reduce lung cancer mortality through 2065

Models Project 79 Percent Drop in Lung CA Mortality by 2065

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Annual number of deaths expected to continue to decrease despite growth, aging of U.S. population
The use of angiotensin-converting enzyme inhibitors is associated with an increased risk for lung cancer compared with angiotensin receptor blockers

Angiotensin-Converting Enzyme Inhibitors May Up Lung CA Risk

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Higher risk seen with ACEIs versus angiotensin receptor blockers; risk linked to duration of use
Durvalumab results in significantly longer overall survival than placebo among patients with stage III

Durvalumab Extends Survival in Stage III Non-Small Cell Lung CA

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Both overall and progression-free survival longer with durvalumab than with placebo
Thermal ablation is a safe

Thermal Ablation Acceptable for Early Lung Cancer

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Regarding overall survival, thermal ablation non-inferior to radiation for primary treatment
Integration of plasma next-generation sequencing into the routine management of metastatic non-small cell lung cancer results in an increase in the detection of therapeutically targetable mutations

Plasma-Based Genotyping Aids Targeted Tx of Metastatic NSCLC

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Most patients who received targeted therapy based on plasma result achieved clinical response
Among patients with anaplastic lymphoma kinase (ALK)-positive non-small cell lung cancer who have not previously received an ALK inhibitor

In NSCLC, Longer Survival With Brigatinib Than Crizotinib

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Longer progression-free survival in those with ALK-positive dz who did not previously take ALK inhibitor
An integrated plasma proteomics classifier

Integrated Classifier Identifies Benign Lung Nodules

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Classifier integrates relative abundance of two plasma proteins with clinical risk prediction model
The quality of shared decision-making about the initiation of lung cancer screening is poor

Poor Shared Decision-Making for Lung Cancer Screening

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Physicians universally recommended screening, with almost no discussion of harms
Broad-based genomic sequencing does not improve survival compared to routine genetic testing among patients with advanced non-small-cell lung cancer

Broad Genetic Testing for NSCLC May Not Improve Survival

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Compared with routine genetic testing, no improvement seen in unadjusted mortality rate