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Tag: Cancer: Leukemia

Polygenic Score Helps Guide Choice of Chemo for Pediatric AML

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Polygenic score based on single nucleotide polymorphisms in the ara-C pathway genes may predict treatment outcomes

Prognostic Index May ID CLL Patients Who Will Not Need Treatment

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Novel prognostic index CLL-WONT identifies patients with chronic lymphocytic leukemia who are at low risk for ever requiring treatment

Overall, Night Shift Work Not Tied to Higher Lymphoma Risk

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However, nonlinear association seen between night shifts and chronic lymphocytic leukemia

Long-Term Outcomes Described for Survivors of Childhood ALL

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Life challenges more negatively impacted in younger, female, relapsed patients; socializing more positively impacted in older patients

Global Burden of Chronic Lymphocytic Leukemia Up From 1990 to 2019

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Incidence higher for men versus women, adults older than 70 years, and individuals living in high social-demographic index regions

Survival Increase Seen for Adults With Relapsed Ph+ ALL

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From 2000 to 2019, overall survival progressively improved for patients with Philadelphia-positive ALL who had posttransplant relapse

Many Hospitals Lack All-Trans Retinoic Acid for Treating Leukemia

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Only 14 percent of hospitals that referred patients with acute promyelocytic leukemia had ATRA readily available

Duration of Maintenance Therapy Studied in Childhood ALL

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Vincristine and dexamethasone pulses might be eliminated during second year of treatment for children with low-risk disease

Ibrutinib + Venetoclax Promising for Chronic Lymphocytic Leukemia

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Seventy-five percent of patients achieved a best response of bone marrow-undetectable measurable residual disease remission

1980 to 2017 Saw Improved Survival for Acute Myeloid Leukemia

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Survival improved across calendar periods for all age groups except for patients aged ≥70 years