Tag: Cancer: Leukemia
AACR: Novel COVID-19 Vaccine Aimed at Immunocompromised Patients
CoVac-1, a peptide vaccine, induces T-cell immune responses in those with B-cell deficiencies, particularly leukemia and lymphoma patients
Ivosidenib + Azacitidine Ups Event-Free Survival in IDH1-Mutated AML
Event-free survival significantly longer compared with placebo and azacitidine for newly diagnosed IDH1-mutated AML
AACR: Resistance Mechanisms to CAR-T Cell Therapy ID’d in ALL
Mechanisms of resistance detectable prior to treatment and include hypermethylation of PCR2 targets in embryonic and cancer stem cells
Durable Remission Seen in Two CLL Patients After CAR T Cell Therapy
CAR T cells detectable more than 10 years after infusion with sustained remission in both patients
Polygenic Score Helps Guide Choice of Chemo for Pediatric AML
Polygenic score based on single nucleotide polymorphisms in the ara-C pathway genes may predict treatment outcomes
Prognostic Index May ID CLL Patients Who Will Not Need Treatment
Novel prognostic index CLL-WONT identifies patients with chronic lymphocytic leukemia who are at low risk for ever requiring treatment
Overall, Night Shift Work Not Tied to Higher Lymphoma Risk
However, nonlinear association seen between night shifts and chronic lymphocytic leukemia
Long-Term Outcomes Described for Survivors of Childhood ALL
Life challenges more negatively impacted in younger, female, relapsed patients; socializing more positively impacted in older patients
Global Burden of Chronic Lymphocytic Leukemia Up From 1990 to 2019
Incidence higher for men versus women, adults older than 70 years, and individuals living in high social-demographic index regions
Survival Increase Seen for Adults With Relapsed Ph+ ALL
From 2000 to 2019, overall survival progressively improved for patients with Philadelphia-positive ALL who had posttransplant relapse