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Tag: Cancer: Leukemia

An experimental therapy for chronic lymphocytic leukemia that uses a patient's own T cells (an approach known as CTL019) may cure some patients and prolong survival in others

Long-Term Remissions of CLL in First Personalized Cell Tx Trial

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T cells reprogrammed to contain chimeric antigen receptor targeting CD19 protein on B cells
Patients with chronic myeloid leukemia who received a glitazone along with imatinib remained disease-free for up to nearly five years in a study published online Sept. 2 in Nature.

Addition of Glitazone to Chemo May Help Treat CML

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Combining glitazones with standard treatment improved survival in small study
Older patients with acute myeloid leukemia are intense users of health care services and rarely use palliative care and hospice services

Older Cancer Patients Heavily Use Health Care Services

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Regardless of chemo intensity, palliative care, hospice rarely used with acute myeloid leukemia
For adult patients with de novo acute myeloid leukemia

Genomic Approach Could Aid Risk Stratification in Adults With AML

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Persistent leukemia-linked mutations in remission samples tied to increased relapse, worse survival
Medicare will pay for a new

Medicare Will Cover Expensive New Leukemia Medication

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Amgen's Blincyto costs about $178,000 for a standard course of treatment
Tyrosine kinase inhibitors appear to be safe in patients with chronic-phase chronic myeloid leukemia and chronic kidney disease

Tyrosine Kinase Inhibitors Seem Safe in CML With CKD

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In these patients, no further decline in GFR, regardless of TKI used
The selective Hedgehog antagonist PF-04449913 seems safe and is tolerated in adults with myeloid malignancies

New Rx for Myeloid Malignancies Moves to Phase II Clinical Trials

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Phase I trial involving 47 patients identified maximum tolerated dose of 400 mg once daily
Breastfeeding is associated with a reduced risk of childhood leukemia compared to the risk for children who were never breastfed

Breastfeeding Tied to Lower Odds of Childhood Leukemia

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One more potential benefit for breastfed babies, research suggests
Two new targeted treatments have shown promise in slowing the progression of recurring chronic-lymphocytic leukemia and slow-growing non-Hodgkin's lymphoma

ASCO: Rx Strategies Promising for CLL, Non-Hodgkin’s Lymphoma

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Ibrutinib, obinutuzumab slow progression of CLL, non-Hodgkin's lymphoma
Adults who were born to older fathers may be at increased risk for blood and immune system cancers such as leukemia and lymphoma

Increased Risk of Cancer Seen for Offspring of Older Fathers

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Higher risk for blood and immune system cancers