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Tag: Cancer: Leukemia

Umbilical cord blood may work as well as current alternatives for adults and children with leukemia -- or even better in some cases

Treating Leukemia With Cord-Blood Transplant Looks Promising

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Donors and recipients don't need to be a perfect match, researcher says
In patients with high-risk relapsed/refractory acute myelogenous leukemia (AML) or untreated AML unfit for intensive chemotherapy

Venetoclax Monotherapy Active in AML With Adverse Features

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Overall response rate 19%; additional 19% have antileukemic activity without meeting IWG criteria
A drug used to treat leukemia

Nilotinib Shows Early Promise for Parkinson’s Disease

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Medication generally found safe, and study findings hint at a benefit
For patients ≥40 years of age with Philadelphia-negative acute lymphoblastic leukemia

HSCT No Better Than Chemo in Philadelphia-Negative ALL

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For patients ≥40 years, HSCT linked to lower cumulative incidence of remission, worse mortality
For patients with acute myelogenous leukemia undergoing induction chemotherapy

Microbiome Linked to Infectious Complications in AML

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Gastrointestinal microbiome diversity linked to infections for patients undergoing induction chemo
There appears to be a strong link between exposure to high levels of radon in the home and women's risk of hematologic malignancies

Radon in the Home Linked to Hematologic Malignancies

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Association seen in women, but no connection found in men
For children and young adults with high-risk B-acute lymphoblastic leukemia

High-Dose Methotrexate Beneficial in Youth With B-ALL

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Superior to Capizzi methotrexate for high-risk B-acute lymphoblastic leukemia
Donor Epstein-Barr virus serostatus influences incidence of graft-versus-host disease in patients with acute leukemia undergoing allogeneic hematopoietic stem-cell transplantation

Donor Epstein-Barr Serostatus Influences GVHD After Allo-HSCT

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Higher risk of acute and chronic GVHD for patients receiving grafts from seropositive donors
Venclexta (venetoclax) has been approved by the U.S. Food and Drug Administration to treat chronic lymphocytic leukemia characterized by a specific chromosomal abnormality

FDA Approves Venclexta for CLL With 17p Deletion

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Drug sanctioned for chronic lymphocytic leukemia in patients with a specific chromosomal abnormality
Emotional distress is common in children during and after therapy for childhood acute lymphoblastic leukemia

Distress Still High After Chemo Completion in Childhood ALL

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Need for targeted early screening, psychosocial interventions to help patients, families at this time