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Tag: Cancer: Leukemia

For patients with FMS-like tyrosine kinase 3 mutations who have relapsed or refractory acute myeloid leukemia

AACR: Longer Survival With Gilteritinib in FLT3mut+ AML

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Longer overall survival, better remission rates seen for patients receiving gilteritinib versus salvage chemo
For children with B-cell precursor acute lymphoblastic leukemia with late bone marrow relapse

Favorable Outcomes Seen in Long Term for ALLR3 Trial

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Findings for risk-stratified tx in B-cell precursor acute lymphoblastic leukemia, late bone marrow relapse
Almost half of elderly patients newly diagnosed with acute lymphoblastic leukemia do not receive treatment

Only About Half of Elderly Newly Diagnosed With ALL Receive Tx

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53.5 percent receive treatment within 90 days; 32.4 percent receive chemo without tyrosine kinase inhibitors
Genetic variations have been identified in the ERG gene that are associated with an increased risk for acute lymphoblastic leukemia in Hispanic children

Genetic Variant Tied to Leukemia Risk in Hispanic Children

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Novel susceptibility locus identified in the ERG gene for acute lymphoblastic leukemia
For children with acute lymphoblastic leukemia

Obesity Linked to Adverse Events in Children With Leukemia

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Obesity ups risk for treatment-requiring hypertension, insulin-requiring hyperglycemia
For some children with hypodiploid acute lymphoblastic leukemia

Addition of BMT Not Indicated in Some With Peds Hypodiploid ALL

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Bone marrow transplant not beneficial if no minimal residual dz after remission induction tx
The risks for therapy-related myelodysplastic syndrome or acute myeloid leukemia are elevated after chemotherapy use for solid tumors

Myelodysplastic Syndrome/AML Risk Increased After Chemo

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Since 2000, risks for therapy-related myelodysplastic syndrome, AML up after chemo for solid cancers

American Society of Hematology, Dec. 1-4

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The 60th American Society of Hematology Annual Meeting and Exposition The annual meeting of the American Society of Hematology was held from Dec....
For older patients with untreated chronic lymphocytic leukemia

ASH: Ibrutinib Tops Bendamustine + Rituximab for CLL

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Improved progression-free survival with ibrutinib for older adults with untreated CLL
Xospata (gilteritinib) tablets were approved today by the U.S. Food and Drug Administration for treatment of relapsed or refractory acute myeloid leukemia (AML) in adults with an FLT3 mutation

FDA Approves Treatment for AML Patients With Gene Mutation

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Expanded approval also granted to mutation assay used to detect FLT3 mutation in AML patients