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Tag: Cancer: Leukemia

Allogeneic hematopoietic cell transplantation with an unrelated donor results in better transplantation outcomes than cord blood transplantation in acute myeloid leukemia patients with active disease

Allo-HCT With Unrelated Donor Tied to Better Outcomes in AML

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In active AML, outcomes superior for allo-HCT with unrelated donor than for cord blood transplantation
Venetoclax-obinutuzumab is associated with longer progression-free survival than chlorambucil-obinutuzumab among patients with untreated chronic lymphocytic leukemia and coexisting conditions

ASCO: Combo Regimen Effective in CLL With Coexisting Conditions

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Progression-free survival longer with venetoclax-obinutuzumab versus chlorambucil-obinutuzumab
For high-risk and older patients with previously untreated chronic lymphocytic leukemia

Ibrutinib, Venetoclax Active in High-Risk, Seniors With CLL

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Findings seen in phase 2 study of combo regimen for first-line treatment of chronic lymphocytic leukemia
Octogenarians with acute myeloid leukemia have a one-month mortality rate of 41 percent and overall survival of 1.5 months

Octogenarians With Acute Myeloid Leukemia Have Poor Survival

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Overall survival 1.5 months; survival improved for those receiving chemotherapy
Venetoclax (VENCLEXTA) has been approved to treat adult patients with chronic lymphocytic leukemia or small lymphocytic lymphoma

FDA Approves Venetoclax for Chronic Lymphocytic Leukemia

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In randomized trial, drug demonstrated statistically significant improvement in progression-free survival
Venetoclax (VENCLEXTA) has been approved to treat adult patients with chronic lymphocytic leukemia or small lymphocytic lymphoma

FDA Approves Venetoclax for Chronic, Small Lymphocytic Leukemia

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In randomized trial, drug demonstrated statistically significant improvement in progression-free survival
For older adults with hematologic malignancies

iADL Dependency May Up Mortality in Hematologic Cancers

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Instrumental activities of daily living dependency, mortality linked in seniors with hematologic cancer
For patients with chronic myeloid leukemia

Reasons for TKI Discontinuation ID’d in Chronic Myeloid Leukemia

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Treatment-free remission maintained in 14 of 21 patients who discontinued tyrosine kinase inhibitors
For patients with acute myeloid leukemia

Presence of Leukemia Cutis Tied to Worse Survival in AML

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Hazard ratios for leukemia-specific death, all-cause death higher for patients with AML and LC
For older patients undergoing allogeneic hematopoietic cell transplantation

Population Mortality Affects Long-Term Follow-Up of AlloHCT

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Substantial part of total nonrelapse mortality for older patients due to population mortality