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Tag: Cancer: Esophageal

Rates of major upper abdominal cancer resections in octogenarians are increasing

Upper Abdominal Cancer Resections Up in Octogenarians

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Increase in resection rates driven by trends in hepatic and pancreatic resections
Adjuvant chemotherapy is associated with improved survival for patients with locally-advanced gastroesophageal adenocarcinoma treated with preoperative chemoradiotherapy and resection

Adjuvant Chemo Beneficial in Advanced Gastroesophageal CA

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Improved overall survival for patients with locally-advanced gastroesophageal adenocarcinoma
For patients with locally advanced esophageal carcinoma who received neoadjuvant chemoradiotherapy

Females Show Better Response to CRT in Esophageal Cancer

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Females more often had complete, nearly complete pathologic response to induction tx; less recurrence
There is a low risk of development of high-grade dysplasia or esophageal adenocarcinoma among patients with Barrett's esophagus of <1 cm (irregular Z line) within five years of index endoscopy

Barrett’s With Irregular Z Line Unlikely to Progress Quickly

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Within five years, incident cancer cases observed only in patients with Barrett's esophagus ≥1 cm
Overweight young adults may have a significantly increased risk of esophageal adenocarcinoma and gastric cardia adenocarcinoma if they become obese later in life

Esophageal Cancer Risk Rises Alongside Weight

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Research also shows association with increased odds for gastric cardia adenocarcinoma
For patients with Barrett's esophagus

No Chemopreventive Effect Seen for H2RAs in Barrett’s Esophagus

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PPI use, but not H2 receptor antagonists, linked to reduced risk of progression in Barrett's esophagus
A breath test to detect esophageal and gastric cancers shows promise

Breath Test to Detect Esophageal, Gastric Cancers May Be Feasible

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Test could reduce the number of unnecessary endoscopies, researcher says

ASCO Gastrointestinal Cancers Symposium, Jan. 19-21

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The 2017 Gastrointestinal Cancers Symposium The American Society of Clinical Oncology's 13th annual Gastrointestinal Cancers Symposium was held from Jan. 19 to 21...
Octamer-binding transcription factor 4 is a predictive marker for patients with digestive system cancers

Oct4 Found to Be a Prognostic Marker for Digestive Cancers

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Elevated Oct4 levels tied to poor overall, disease-free, and recurrence-free survival
In guidelines published online Nov. 14 in the Journal of Clinical Oncology

Guidelines Developed for HER2 Testing in Gastroesophageal CA

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Tumor specimens should be assessed for HER2 status before initiation of HER2-targeted therapy