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Tag: Cancer: Colon

Colon tumors that don't produce the protein CDX2 are more likely to recur following surgical removal in patients with stage II colon cancer

CDX2-Negative Colon Cancer May Need More Tx Post Surgery

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Patients with CDX2-negative tumors more likely to benefit from chemo in addition to surgery
For patients with stage III colon cancer treated with leucovorin

KRAS, BRAF V600E Mutations Impact Survival in Colon Cancer

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Mutations linked to shorter survival in patients with microsatellite-stable tumors
Dietary glutamic acid intake is associated with reduced risk of developing colorectal cancer

Dietary Glutamic Acid Linked to Lower Risk of Colorectal Cancer

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Significant reduction in risk for participants with body mass index of ≤25 kg/m²
Vistogard (uridine triacetate) has been approved by the U.S. Food and Drug Administration to treat an overdose of the chemotherapy drugs fluorouracil and capecitabine

FDA Approves Vistogard to Treat Chemotherapy Overdose

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For overdose of the chemo drugs fluorouracil and capecitabine
A citywide colon cancer control coalition can increase colorectal cancer screening and address health disparities

Citywide Colon Cancer Control Coalition Ups Screening in NYC

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Efforts of coalition increased screening colonoscopy from 42 percent in 2003 to almost 70 percent in 2014
Colorectal neoplasm is associated with smoking in a dose-response manner

Dose-Response Pattern for Smoking, Colorectal Neoplasm

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Increase in non-advanced, advanced CRN with increasing smoking; no link for alcohol intake
For patients enrolled in metastatic colorectal cancer trials

Low BMI Linked to Increased Risk of Progression, Death in mCRC

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Risk of progression and/or death highest for low BMI, decreases as BMI increases, then plateaus
Continuing a centralized mailed fecal occult blood test program is beneficial for improving adherence to colorectal cancer screening

Continuing Mailed FOBT Program Ups CRC Screening Adherence

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Continuing benefits for patients who completed FOBT tests in years one and/or two of the program
Processed meats

WHO: Evidence That Processed Meat Can Cause Cancer

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Meanwhile, red meat only shows some association with an increased risk for colorectal cancer
For patients with colorectal cancer

SNORA42 Identified as Novel Oncogene in Colorectal Cancer

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Increased SNORA42 expression is independent prognostic factor for overall, disease-free survival