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Tag: Cancer: Colon

ASCO Gastrointestinal Cancers Symposium, Jan. 19-21

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The 2017 Gastrointestinal Cancers Symposium The American Society of Clinical Oncology's 13th annual Gastrointestinal Cancers Symposium was held from Jan. 19 to 21...
For patients undergoing colorectal cancer surgery

CpG Island Methylator Phenotype Prognostic After CRC Surgery

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CIMP-high is significant prognostic factor in multivariate analysis for patients after CRC resection
Just a half hour a day of moderate physical activity could improve survival odds for patients with metastatic colorectal cancer

ASCO: Moderate Activity Tied to Longer Survival in Advanced CRC

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Patients only appeared to derive benefit from moderate -- not vigorous -- activity
As many as one in six colorectal cancer patients under the age of 50 have genetic traits that greatly increase the risk of cancer

CRC in Patients Under 50 Often Caused by Genetic Mutations

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One in six diagnosed under 50 have at least one gene mutation that ups risk of cancer
Administration of cytotoxic T-cells targeting mutant KRAS G12D can induce tumor regression in metastatic colorectal cancer

Cytotoxic T-Cells Can Induce Metastatic CRC Regression

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Regression of tumors reported after administration of cytotoxic T-cells targeting mutant KRAS G12D
Statins seem not to be associated with the risk of colorectal adenoma

Meta-Analysis: Statins Cut Risk of Advanced Colorectal Adenoma

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In meta-analysis, statin use linked to reduced risk of advanced, but not any colorectal adenoma
Octamer-binding transcription factor 4 is a predictive marker for patients with digestive system cancers

Oct4 Found to Be a Prognostic Marker for Digestive Cancers

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Elevated Oct4 levels tied to poor overall, disease-free, and recurrence-free survival
Regular aspirin use is associated with a lower risk of colorectal carcinomas with low concentrations of tumor infiltrating lymphocytes

Immune Response May Be Key to Chemopreventive Effect of Aspirin

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Link seen for colorectal tumors with low levels of tumor infiltrating lymphocytes
Colorectal cancer detected after colonoscopy examination is more often located in the proximal colon and more likely to have DNA mismatch repair deficiency

CRC Detected After Colonoscopy Often Located in Proximal Colon

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Tumors more likely to have DNA mismatch repair deficiency, less likely to be metastatic
Weight loss following chemically-induced carcinogenesis is not beneficial for colon and liver carcinogenesis in a mouse model that mimics human obesity

Weight Loss May Not Benefit Colon, Liver Cancer

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In experimental study, no impact on colon tumorigenesis; may negatively impact liver repair