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Tag: Cancer: Colon

Hot Spots ID’d for Higher CRC Mortality in Younger Women

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Nearly one in 16 U.S. counties are hot spots, with the majority in the South

Pembrolizumab Slows MSI-H-dMMR Metastatic CRC

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Pembrolizumab superior to chemo for progression-free survival among patients who had not previously received treatment

Colon Cancer Diagnosed Earlier Under Medicaid Expansion

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Medicaid expansion also may result in improved access to treatment, including palliative care

Laparoscopic Resection May Be An Option for CRC Liver Metastases

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For resectable colorectal liver metastases, five-year survival rates similar with laparoscopic, open surgery

Surgeon Skill Level Tied to Colon Cancer Surgery Survival

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Highly skilled surgeons may boost colon cancer survival by 70 percent

The U.S. Preventive Services Task Force (USPSTF) concludes that there is a substantial net benefit for screening adults age 50 to 75 years for colorectal cancer and moderate net benefit for adults ages 45 to 49 years. These findings form the basis of a draft recommendation statement published online Oct. 27 by the USPSTF.

USPSTF Issues Draft Recommendation for CRC Screening

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Benefit substantial for adults aged 50 to 75 years; benefit moderate for adults aged 45 to 49 years
Decreased colorectal cancer incidence is seen in association with use of aspirin

Review IDs Dietary Factors Linked to Lower CRC Incidence

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Incidence up with frequent alcohol or meat consumption; no evidence of protective effect found for tea, coffee
Many patients with biopsy-confirmed advanced colorectal polyps are unaware of their need for repeat colonoscopy as well as the proper surveillance interval

High-Risk Patients Not Aware of Needed Colonoscopy Intervals

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Findings among patients with biopsy-confirmed advanced colorectal polyps
For patients with familial adenomatous polyposis

Eflornithine + Sulindac Shows No Benefit in Adenomatous Polyposis

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Incidence of disease progression not significantly lower with combo versus either drug alone
The use of angiotensin converting enzyme inhibitors and angiotensin receptor blockers is associated with lower risk of colorectal cancer risk that develops within three years after index colonoscopy

CRC Risk Down With ACEi, Angiotensin Receptor Blocker Use

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5 percent reduction in adjusted hazard ratio risk with each single year increase in drug use