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Tag: Cancer: Cervical

The proportion of human papillomavirus 16/18-positive cervical intraepithelial neoplasia grades 2 to 3 or adenocarcinoma in situ declined from 2008 to 2014

Decline Observed in HPV Type 16/18 Cervical Precancers in U.S.

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Greatest declines seen among vaccinated women; decreases also seen in unvaccinated women
In the absence of further intervention

44.4 Million Estimated to Be Diagnosed With Cervical Cancer by 2069

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From 2020 to 2069, 6.7 to 7.7 million cases could be averted by scaling up HPV vaccination by 2020
A deep learning-based visual evaluation algorithm can detect cervical precancer/cancer with higher accuracy than conventional cytology

Algorithm Evaluates Cervical Images to ID Precancer, Cancer

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Deep learning-based algorithm was validated using archived, digitized cervical screening images
Less than two-thirds of eligible 30- to 65-year-old women are up to date with cervical cancer screening

Cervical Cancer Screening Rates ‘Unacceptably Low’

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Just 64.6 percent of 30- to 65-year-old women up to date, but Pap-HPV cotesting has increased
The presence of certain high-risk human papillomavirus types predicts future risk for high-grade cervical cancer even among women with no cellular indications of cancer at baseline

HPV Ups Cervical Cancer Risk, Even With No Cellular Signs

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HPV-16/18 confers strong future risk, particularly in women younger than 30 years
Continuing regular cytology screening up to age 75 years or performing an exit human papillomavirus (HPV) test to confirm the absence of oncogenic HPV strains past the age of 55 years offers preventive benefit for older women with a cervix

Age to Stop Cervical Cancer Screening Depends on Test Used

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Negative HPV test, HPV-cytology co-test tied to low remaining lifetime cancer risk for unvaccinated
For patients with early-stage cervical cancer

Minimally Invasive Sx May Up Mortality in Early Cervical Cancer

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Two studies show increased mortality and reduced disease-free, overall survival versus open surgery
Women with high-risk human papillomavirus (hrHPV)-positive cervical tumors have a substantially better prognosis than women with hrHPV-negative tumors

Positive HPV Status Tied to Better Cervical Cancer Prognosis

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Five-year relative survival ratio better for hrHPV-positive cases than for hrHPV-negative cases
Catch-up doses of quadrivalent human papillomavirus vaccination are effective for girls and women aged 14 to 20 years at the time of first dose

Catch-Up HPV Doses Effective to Age 21 Against Cervical Neoplasia

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But catch-up doses not effective against CIN for women who initiated vaccination at 21 to 26 years
The U.S. Preventive Services Task Force has updated the recommendations for screening for cervical cancer; the final recommendation statement has been published in the Aug. 21 issue of the Journal of the American Medical Association.

USPSTF Updates Guidance for Cervical Cancer Screening

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Cytology recommended every three years from age 21; different screening options from age 30 to 65